超脉冲CO2激光联合调Q532nm激光治疗老年斑及老年疣的的疗效观察.docVIP

超脉冲CO2激光联合调Q532nm激光治疗老年斑及老年疣的的疗效观察 　　[摘要]目的：探讨超脉冲CO2激光联合调Q532nm激光治疗老年斑及老年疣的临床疗效及安全性。方法：实验组：306例，使用调Q532nm激光联合超脉冲CO2激光治疗；对照1组：302例，单独使用超脉冲CO2激光治疗；对照2组：305例，单独使用调Q532nm激光治疗。疗程结束后对其临床效果及安全性进行评价。结果：实验组患者老年斑及老年疣一次治疗后治愈率95.8%，暂时性色素沉着发生率12.2%，未见色素减退及瘢痕。与对照组两两比较均有显著性差异（P0.05）。结论：超脉冲CO2激光联合调Q532nm激光治疗老年斑及老年疣临床疗效显著，安全性较高。 　　[关键词]超脉冲CO2；Q532nm；老年斑；老年疣 　　[中图分类号]R364.2+3 [文献标志码]A [文章编号]1008-6455（2015）09-0040-03 　　Abstract： Objective To investigate combined with the ultra-pulsed CO2 laser and Tune Q532nm laser to treat the pigmentation disease， and to evaluate the clinical efficacy and safety of combination therapy. Methods From January 2011 to January 2014 in our beauty laser center department of 913 cases of senile plaques and senile warts treatment of 306 cases of patients are used in combination with tune Q532nm laser and ultra pulse CO2 laser.Control group selected separately using ultra pulse CO2 laser treatment of 302 cases of patients， and independently used adjustable Q532nm laser treatment of 305 cases of patients.Combined with the ultra-pulsed CO2 laser and Tune Q532nm laser treat the patients of senile plaques and thickening senile warts， and to evaluate its clinical efficacy and safety. Results After one time treatment for the experimental group patients of senile plaques and senile warts，the cure rate was 95.5%，temporary hyper pigmentation incidence of 12.2%，no hypo pigmentation and scarring.Compared with the control group was significantly different （P0.05 ）. Conclusion The therapy of combined with variety of laser such as the ultra-pulsed CO2 laser and tune Q532nm laser for skin pigmentation diseases， made significant clinical efficacy with higher security. 　　Key words：ultra-pulsed CO2；Q532nm；senile plaques；senile warts 　　老年斑及老年疣均为脂溢性角化病，又称基底细胞乳头瘤，是良性表皮性肿瘤， 主要是不饱和脂肪酸和蛋白质结合产生脂褐素沉积所致， 大多发生于老年人， 亦可见于青年人[1-2]。其特点是具有明显分界的褐色斑块与疣状表面，发病机制还不明确[3]。早期表现为扁平丘疹或斑片，淡褐或深褐色，表面光滑，称之为老年斑；后逐渐增大隆起，表面可呈轻度乳头瘤样增生，常附有油腻性鳞屑，病程缓慢，无自愈倾向，称之为老年疣。传统的治疗方法多采用超脉冲CO2激光，本研究在传统方法的基础上联合使用调Q532n