黄芪注射液治疗慢性充血性心力衰竭56例的的疗效观察.docVIP

黄芪注射液治疗慢性充血性心力衰竭56例的的疗效观察 　　作者单位：274000 山东省菏泽市牡丹区王浩屯镇中心卫生院（刘广才）；山东省菏泽医学专科学校（郜宪林） 　　通讯作者：刘广才 　　【摘要】 目的 观察黄芪注射液配合西药常规治疗慢性充血性心力衰竭的疗效及安全性。方法 110例患者随机分成对照组和治疗组,对照组54例给予西医常规抗心力衰竭治疗,治疗组56例在常规抗心力衰竭的基础上加用黄芪注射液40 ml ，1次/d,两组均连续用药2周。结果 临床疗效总有效率治疗组为91.07%，对照组为72.22%；心电图改善总有效率治疗组为87.50%，对照组为62.96%。两组在临床疗效和心电图改善方面均有显著差异（P0.05）,治疗组明显优于对照组。结论 黄芪注射液配合西医常规抗心力衰竭治疗慢性充血性心力衰竭,比单纯西医常规治疗效果好，是非常有前景的治疗心力衰竭药物。 　　【关键词】 慢性充血性心力衰竭; 黄芪 　　Clinical study on astragalus injection in treating chronic congestive heart failure 56 cases LIU Guang-cai*,GAO Xian-lin.*The Health Center of Wanghaotun in Heze,Heze 274000,China 　　【Abstract】 Objective To observe the clinical effect and safety of Astragalus Injection combine with routine treatment in treating chronic congestive heart failure （CHF）.Methods 110 patients of CHF were randomly divided into two groups.56patients of the treatment group and 54 patients of the control group were all received routine medicine，at the same time，the treatment group was administered Astragalus Injection 40ml/d.The therapeutic course was two weeks.Results The Total clinical effective rate in the treatment group and the control group was 91.07% and 72.22% respectively.The total effective rate of ECG in the treatment group was87.50%and 71.43% in the control group; Both the treatment group and the control group had significant difference in the clinical efficiencies and electrocardiogram efficiencies （P 0.05） .The treatment group was significantly better than the control group.Conclusion Astragalus Injection combine with conventional anti-HF therapy for treating CHF has affirmatively curative effect,and also it is a very promising durg used intravenously in heart failure. 　　【Key words】 Chronic congestive heart failure; Astragalus 　　 　　慢性充血性心力衰竭（CHF）是指心脏由于收缩和（或）舒张功能严重低下或负荷过重，使泵血明显减少，不能满足全身代谢需要而产生的临床综合征，包括动脉系统供血不足和静脉系统淤血甚至水肿，伴有神经内分泌系统激活的表现［1］。祖国医学认为，《素问 逆调论》：“夫不得卧，卧则喘者是水邪之客也”。张仲景《金贵要略 水气病脉证并治第十四》论述五脏水肿：“心水者，其身重而少气，不得卧，烦而躁，其人阴肿”。应归属于“心悸”“怔忡”“喘证”“水肿”等范畴。故临床上强调扶正固本、益气养血、提高正气