老年冠心病患者下肢动脉硬化危险因素剖析.docVIP

老年冠心病患者下肢动脉硬化危险因素剖析 　　[摘要] 目的 探讨影响老年冠心病患者下肢动脉硬化闭塞症（LEASD）发生发展的相关危险因素。 方法 选择2014年1～3月哈尔滨医科大学附属第四医院冠心病患者114例为研究对象，采用彩色多普勒超声观察下肢血管狭窄程度，根据狭窄程度将其分为狭窄率≥70%组（n=21）和狭窄率 0.05）。④Logistic分析表明老年LEASD患者下肢血管狭窄率≥70%与高龄（90岁）、高血压、糖尿病、HDL-C降低、HHCY、hs-CRP增高密切相关（P=0.033、0.036、0.021、0.028、0.034、0.046）。 结论 ①70岁以上老年冠心病患者下肢动脉硬化发生率高达64.9%；② LEASD血管狭窄程度与年龄具有一定的相关性；③高龄（90岁）、高血压、糖尿病、HDL-C降低、HHCY、hs-CRP增高是预测老年冠心病患者下肢动脉硬化狭窄率≥70%的独立危险因素。 　　[关键词] 下肢动脉硬化；老年冠心病；危险因素；相关性 　　[中图分类号] R541 [文献标识码] A [文章编号] 1673-7210（2014）08（c）-0044-04 　　Analysis of risk factors of senile coronary heart disease with arteriosclerosis obliterans 　　ZHANG Xiaobo YU Junmin WANG Huidong JIANG Wen LI Dahe HU Shuang CHEN Hongye 　　The First Geriatrics Ward， the Fourth Affiliated Hospital of Harbin Medical University， Heilongjiang Province， Harbin 150001， China 　　[Abstract] Objective To investigate the risk factors affecting the occurrence of senile coronary heart disease （CHD） with lower extremity atherosclerosis disease （LEASD）. Methods 114 cases of patients with CHD from February to January 2014 in the Fourth Affiliated Hospital of Harbin Medical University were selected as study objects， the stenosis degree of lower extremities vascular of all patients were observed by color doppler flow imaging， and they were divided into two groups according the degree of stenosis， stenosis rate 0.05）. ④Logistic regression analysis showed that the elder （90 years）， hypertension， diabetes， low level of HDL-C， HHCY， high level of hs-CRP were closely related with older patients with LEASD whose stenosis≥70% （P = 0.033， 0.036， 0.021， 0.028， 0.034、0.046）. Conclusion ①The incidence rate of lower limb arteriosclerosis is 64.9% in the patients of CHD over 70 years；②vascular stenosis of LEASD is related with age；③hypertension， age90， diabetes， low level of HDL-C， HHCY， high level of hs-CRP are independent risk factors in prediction of elderly patients with CHD occurred lower limb atherosclerosis stenosis rate≥70%. 　　[Key words] Lower extrem