健胃清幽片治疗幽门螺杆菌相关消化性溃疡的临床与实验研究-中医内科学专业论文.docxVIP

援 援 要 本文鏊在运焉中鞋帮中礴薮缀合理论，扶理论、簸凑粒安羲研究诸方 面探讨幽门螺孝下菌相关消化能溃疡的病因病机、治疗原则及中药健胃清幽 片的疗效机理。研究表明，HP相关消化性溃疡的基本病机是本廪标实，实 邪感染为其标，脾胃虚弱为其本。立法健脾益胃扶『F、清热解海祛邪。组 方健胃清幽片。临床研究表明：健胃清幽片治疗HP相关溃疡瘸瘢状总有 效率94．0％，消化性溃疡有效率87．1％，均高于对照组78．3％、69．9％。 HP总抑杀率治疗组83．0％，对照纽8l。7％，两者相似。实验研究褒明：健 霉湾壅片在撺杀HP懿间戆，霹滠窝免疫功瞧著改善霉穗膜激环缓，增强 缀织骖复藐力，逶过改善黉越徽绦稳，鬟裹懿薅兔疫力，竣窝HP赖渡生 存的条件，从而这戮键避溃疡愈合，羰少复发的作用，其标本蘸治、价格 低廉、服用方便的特点。 关键词：消化性溃疡；幽门螺杆菌；健胃清幽片；临床研究；实验研 究． The The Cl i nicaI and Exper imentat Research on Treati ng H．PYIor i associated PeptiC UI er Di sease with tabI et of di anwei qi ngyoupi an Author： Tutor： Speci aIty： Mediei Re of TCM Abstract We have inquired into the etiology and pathogenesis of H，pylori associated Peptic uler disease and its treating principle by using the theory of Traditional Chinese Medicine(TCM)and combination of TCM and Western Medicine．By means of clinical and experimental researches，we have explored the mechanism of the curative effect of Jianweiqingyoupian on H。 pylori associated peptic uler di sease．We found that the fundamental pathogenesis H．pylori associated Peptic uler disease is the deficiency in its principal aspects and the excess in its secondary aspects．The exogenous pathogenic factors is exterior and qi deficiency in the spleen and stomach is its interior．Therapeutic methods：Strengthening anti·pathogenic qi and eliminating pathogenic factors．Prescription：Tablet of Jianweiqingyoupian． The result of clinical research showed that the treatment group had 94．0 percent in effective ate and 87．iO percent in the alleviated rate of Peptic uler disease，superior to contrast group with 78。30 percent and 69．90 percent respectively．Treatment group is similar to contrast group in killing HP rate， the former is 83．00 percent and the latter is 81．70 percent．The experimental research indicated that Jianweiqingyoupian can increase immune functions， improve tissue，therefore decrease relapse of Peptic uler disease。 Key words：Pept{c ule r di sease：H．PYlori：TabIet of di anwei qI ngyoupj an：CI i ni ca