甲状旁腺功能减退症临床分析-内分泌专业论文.docxVIP

浙江大学2007硕士学位论文作、精神症状、血钙降低、血磷升高、除假性甲旁减外血PTH均降低。给予补钙 浙江大学2007硕士学位论文 作、精神症状、血钙降低、血磷升高、除假性甲旁减外血PTH均降低。给予补钙 治疗后症状缓解。 结论 甲状旁腺功能减退症是由各种原因引起的甲状旁腺激素减少或结构异常或 靶器官对其不反应的疾病。分特发性甲旁减、手术后甲旁减、假性甲旁减，共同 表现为低钙血症，治疗原则是纠正低血钙。 【关键词】甲状旁腺功能减退症；诊断；治疗。 3 浙江大学2007硕士学位论文Clinical 浙江大学2007硕士学位论文 Clinical analysis of hypoparathyroidism Endocrinology and metabolic disease,the Medical coUege of Zhejiang University Postgraduate Grade 2004：REN Fang Supervisor．SHEN Jian-guo Abstract Background and objective Hypoparathyroidism is the endocrine system disease which causes may include reduction of PTH,abnormal structure of parathyroid glands and the target organ no response to P掰．The COmmon clinical manifestation is tetany,hypocalcemia and hypcrphosphateraia．Etiology could be divided into three aspects：(1)parathyroid gland imjured after thyroid or parathyroid surgery；(2)idiopathic,maybe related to autoimmunity disfunction； (3)very few due to genetic deficiency．Disease incidence is low,and clinical manifestation is often complicateSo this disease is easy to be misdiagnosed．This article is designed to report the type，clinical manifestation，diagnosis and treatment of 22 patients with hypoparathyroidism． Methods The clinical data of 22 patients with hypoparathyroidism admitted to our hospital from 2000 to 2006 were analyzed renospeetivdy．We collected the clinical features(age， sex,course of disease，symptom,physical examination and灯eatI】艟nt)，au】‘iliary examination (blood calcium,blood phosphonium，24 hour urina calcium and phosphonium,blood PTH，EKG, cranium CT or加呱EEG)．Cfinical manifestation,diagnosis and treatment wcrc analyzed and compared． Results 22 cases etiologically included 13 idiopathic hypoparathyroidism，8 postsurgical 4 浙江大学2007硕士学位论文 浙江大学2007硕士学位论文 hypoparathyroidism and 1 pseudohypoparathyroidism．Tetany, epilepsy,neuro- psychiatrical symptoms,hypocalcemia,hyperphosphatemia wcrc：common clinical manifestation．There was also low lcvcl of mL except pscudohypoparathyroidism． After treated with calcium，