胎粪吸入综合征并发新生儿肺出血58例临床研究.docxVIP

胎粪吸入综合征并发新生儿肺出血58例临床研究 【摘要】目的：探讨应用肺表面活性物质联合机 械通气治疗胎粪吸入综合征并发新生儿肺出血的临床意义。 方法：对本院新生儿重症监护室2008年10月-2012年10月 共收治的58例胎粪吸入综合征并发新生儿肺出血的患儿给 予肺表面活性物质联合机械通气治疗，对其临床资料进行回 顾性分析。结果：58例肺出血新生儿中，存活38例（65. 5%）, 死亡11例（18. 9%）,放弃治疗9例（15.5%）。存活新生儿 平均机械通气治疗时间71 h （最短21 h,最长128 h）o结 论：以应用肺表面活性物质联合机械通气的综合治疗是胎粪 吸入综合征并发新生儿肺出血的主要治疗措施。 【关键词】胎粪吸入综合征；新生儿肺出血；肺表 面活性物质；机械通气 Clinical Analysis on Fifty-Eight Cases with Meconium Inhaled Syndrome Complicated with Neonatai Pulmonary Hemorrhage/LI Jie, GU Xian-fang .//Medical Innovation of China, 2014, 11 （01 ）： 134-135 [Abstract] Objective： To discuss the clinical significance of application of lung surface active substance combined with mechanical ventilation treatment of the meconium inhaled syndrome complicated with neonatai pulmonary hemorrhage? Method : Collecting 58 cases with neonatal meconium inhaled syndrome complicated with lung hemorrhage in Neonatal intensive care unit in our hospitol from October 2008 to October 2012, and they were given lung surface active substances with mechanical ventilation therapy. The clinical data was retrospectively analyzed. Result : In 58 cases with pulmonary hemorrhage in newborns, 38 patients survived (65.5%), 11 cases died (18.9%), 9 cases gave up treatment (15.5%)? The average time of mechanical ventilation of live births was seventy-one hours (the shortest was twenty-one hours, the 1ongest was one hundred and twenty-eight hours) . Conelusion： The application of lung surface active material joint mechanical ventilation is primary treatment of meconium inhaled syndrome complicated with neonatai pulmonary hemorrhage? [Key words 】 Meconium inhaled syndrome； Neo natal pulmonary hemorrhage； Lung surface active substance； Mechanical ventilation First—authot s address : Kaifeng Children ? s Hospital, Kaifeng 475000, China doi： 10. 3969/j. issn. 1674-4985.2014.01.063 胎粪吸入综合征 (meconium aspiration syndrome, MAS)是导致新生儿死亡的一种常见疾病，发病率占成活新 生儿1.2%?2. 2%,病死率7%?15. 2%[l]o其中并发肺出血 是导致死亡的主要原因。本院新生儿重症监护室2008年10 月-2012年10月共收治胎粪吸入综