课件：BN在心衰诊断中的应用.ppt

* This graph demonstrates the relationship of BNP values to the severity of the CHF. BNP concentrations increased as the severity of the disease increased. The Triage? BNP Test is indicated for use as an aid in the diagnosis of congestive heart failure. * BNP concentrations were higher for patients admitted to the hospital versus discharged patients, also consistent with the relationship between BNP and disease severity. The Triage? BNP Test is indicated for use as an aid in the diagnosis of congestive heart failure. * In this trial, 30 patients were misdiagnosed by the ED physician who was blinded to the BNP level. 15 of these patients were considered to not have congestive heart failure (under-diagnosed) who were later diagnosed with CHF. In addition, 15 patients were considered to have congestive heart failure who did not (over-diagnosed). 97% (29 out of 30) of these patients would have been accurately diagnosed had the blinded BNP result been available. The Triage? BNP Test is indicated for use as an aid in the diagnosis of congestive heart failure. * Utility of B-type natriuretic peptide in the diagnosis of congestive heart failure in an urgent-care setting. Dao Q, Krishnaswamy P, Kazanegra R, Harrison A, Amirnovin R, Lenert L, Clopton P, Alberto J, Hlavin P, Maisel AS. Department of Medicine, Veterans Affairs Medical Center, San Diego, California, USA.OBJECTIVES: The goal of this study was to evaluate the utility of a rapid bedside technique for measurement of B-type natriuretic peptide (BNP) in the diagnosis of congestive heart failure (CHF) in an urgent-care setting. BACKGROUND: B-type natriuretic peptide is a protein secreted from the cardiac ventricles in response to pressure overload. One potential application of measurements of BNP in blood is distinguishing dyspnea due to CHF from other causes. METHODS: B-type natriuretic peptide concentrations were measured in a convenience sample of 250 predominantly male (94%) patients presenting to urg