囊虫散胶囊治疗脑实质型脑囊尾蚴病的临床研究.docxVIP

囊虫散胶囊治疗脑实质型脑囊尾呦病的临床研究* 郑九红，廉辰 (邯郸市中医院，河北邯郸056001) 【摘要】目的观察囊虫散胶囊治疗脑实质型脑囊尾蝴病的临床疗效。方法：选择脑实质 型囊尾坳病300例，随机分为3组，分别用毗卩奎酮，囊虫散胶囊及囊虫散胶囊+毗U奎酮治疗， 对疗效、不良反应、治疗前后囊尾蝴钙化灶变化进行对比分析；囊虫散注射皮肌囊尾蝴结节， 观察囊虫散胶囊杀灭囊尾呦作用。结果 囊虫散胶囊组治愈率82.1%,毗嗪酮组治愈率 67.4%,中西药结合组87.6%,差异有显著性(PV0.01)。不良反应发生率，囊虫散胶囊组最 低。囊虫散注射皮肌囊尾蝴结节，杀虫总有效率为97.6% (41/42)o结论囊虫散胶囊治 疗脑实质型脑囊尾蝴病效果显著，不仅具有杀虫作用，同时促进死虫吸收，而II毒副作用小， 安全可靠。 【主题词】脑囊尾勉病；脑实质型；中药治疗；囊虫散胶囊 Clinical observation on the treatment of cerebral systicercosis with Nangchongsan capsule.ZHENG Jiu-hong, LIAN Chen.(HandanMunicipal Traditional Medicine Hospital ,Handan 056001,Hebei,P.R.China) [Abstract] Objective To observe the clinical effect of Nangchongsan capsule on perenchymatous cerebral systicercosis. Methods Three hundred parenchymatous systicercosis patients were selected and randomly and parallely divided into three groups, namely the Nangchongsan Group, Western and Traditional Chinese Medicine Group and Weater Medicine Group. The results of therapeutic effect, poisonous and aside effects, the imaging variations of catcified foci of systicercosis patients were analyzed? The effect of Nangcongsan in killing systiverci was also observed. Results The cure rates in Nangchongsan Group, Praziquantel Group, Western and Traditional Medicine Group were 82.1 %, 67.4%, 87.6%.respectively, showing significant differences (p0.01).The adverse reactions in Nangchongsan Group was the lowest and the curative effect was the best as compared with the other tow groups. Conclusion The effect of Nangchongsan capsule on cerebral parenchymatous cerebral systicercosis is significant, it can not only kill systicerei but also promote the absorption of dead parasites with light side effect ang high Scifety. Key words:Cerebral systicercosis; Traditional Chinese medicine; Nangchongsan capsule 脑囊尾坳病严重危害患者的神经系统，临床将其分为脑实质型、脑室型、脑膜型、混合 型4型⑴。脑实质型又进一步分轻、屮、重度3个业型，其屮屮度脑实质型囊尾蝴病较为常 见，且病情较重，治疗风险大。囊虫散胶囊是我院应用多年的医院自制剂，对各型脑囊尾蝴病 均有显著效果。本研究系统观察了中药囊虫散胶囊治疗中度脑实质型脑囊尾坳病的临床疗 效，并进行了注射囊虫散胶囊杀灭皮肌囊尾蝴的实验观察。 【基金项目】国家中医“十五”重点专科建设经费资助