昆脂愈肤灵治疗糖尿病足的疗效观察.docVIP

GIP Chinese General Practice 2010年12月第13卷第12C期 ·4133 · · 短 篇 论 著 · 昆脂愈肤灵治疗糖尿病足的疗效观察 吴卫平，房辉，田金莉，张雅中，张禾伟，许静，王爱媛，张谷月，张丹丹，安彩霞，杨岳 【摘要】 目的 观察昆脂愈肤灵治疗糖尿病足的临床疗效。方法 选取69例糖尿病足患者，均为2型糖尿病。 将患者随机分为两组：昆脂愈肤灵组(35例)和对照组(34例)。除了控制血糖、抗生素控制感染、支持治疗、纠正 贫血和低蛋白血症、创面常规治疗外，昆脂愈肤灵组还用昆脂愈肤灵敷于创面，对照组还用无菌纱布贴敷于创面。观 察治疗前后两组患者的血糖水平及创面愈合情况。结果 治疗后两组患者血糖水平均较治疗前显著降低 (P0.05), 但组间差异无统计学意义 (P0.05)。 治疗后昆脂愈肤灵组患者溃疡面愈合时间〔(41.2±2.6) d〕 较对照组 〔(56.1±2.8)d〕 显著缩短，差异有统计学意义 (P0.05); 且治疗后昆脂愈肤灵组的有效率(100.0%)显著高于 对照组(85.3%),差异有统计学意义 (P0.05)。 结论 昆脂愈肤灵联用胰岛素强化治疗糖尿病足可加速创面早日 愈合，缩短病程，为糖尿病足的内科治疗提供了一种可行性治疗方法。 【关键词】 糖尿病足；足溃疡；昆脂愈肤灵；治疗结果 【中图分类号】 R587.29 【文献标识码】 B 【文章编号】1007-9572(2010)12-4133-02 The Clinical Effects of Curessd Wound Dressing in Treating Diabetes Mellitus Pedal Patients WU Wei-ping,FANG Hui, TIAN Jin-li,et al. Department of Endocrinology, the Workers Hospital of Tangshan, Tangshan 063000,China 【Abstract] Objective To observe the clinical curative effect of curessd wound dressing in the treatment of diabetes foot. Methods 69 diabetes foot patients were selected, who were all type 2 diabetes. Patients were randomly divided into curessd wound dressing group (35 patients)and control group (34 patients). In addition to controlling blood sugar, controlling infection by antibiotics, supporting treatment,correcting anemia and hypoalbuminemia and wound routine treatment,curessd wound dressing group used curessd wound dressing and the control group also spread sterile gauze mask to the wound. Then ob- serve the changes on plasma glucose and the wound healing. Results After treatment, the two groups blood glucose levels re- duced significantly(P0.05). But the difference between the two groups was not significant(P0.05). After treatment,ul- cer surface healing time of curessd wound dressing group 〔(41.2±2.6)d〕 was significantly shorter〔(56. 1±2.8)d〕 com- pared with the control group(P0.05); Efficacy of the curessd wound dressing group was significantly higher compared with the control group(P0.05).