动态血糖监测系统在改善老年2型糖尿病患者血糖控制中的应用.docVIP

·465 · · 论 著 · 动态血糖监测系统在改善老年2型糖尿病患者 血糖控制中的应用 钟远，章晓燕，胡廷军 【摘要】 目的 探讨动态血糖监测系统 (continuous glucose monitoring system,CGMS) 在老年2型糖尿病患者降 糖治疗中的指导作用。方法 选取200例老年2型糖尿病患者，随机分为强化血糖监测组 (CGMS 组)和常规血糖监 测组 (self-monitoring of blood glucose,SMBG组)。 CGMS 组患者行3 dCGMS 监测， SMBG 组采用八点法测定血糖值， 分别根据各自血糖监测结果调整治疗方案，2周后两组患者均佩戴3 dCGMS。 比较两组患者血糖控制情况，同时比较 CGMS 组治疗前后血糖波动情况。 结果 CGMS 组患者血清糖化清蛋白 (GA)、 平均血糖水平 (MBG) 、 平均血糖漂移 幅度 (MAGE) 〔分别为(17.0±2.9)%、(7.5±3.2) mmol/L、(3.2±1.0)〕 显著低于SMBG 组〔分别为(18.5± 4.1)%、(9.9±3.0)mmol/L、 (5.6±2.1)〕。CGMS 组调整治疗后GA、MBG、MAGE 较治疗前〔分别为(21.8± 5.0)%、(11.6±3.6)mmol/L 和(5.5±1.1)〕显著下降，差异有统计学意义 (P0.05)。 结论 CGMS 监测血糖调 整治疗后患者血糖控制情况显著优于常规监测的患者；根据CGMS 结果调整治疗方案后患者血糖波动情况明显改善， CGMS 是改善血糖控制效果的有效工具。 【关键词】 动态血糖监测；糖尿病，2型；血糖自我监测 【中图分类号】 R587.1 【文献标识码】 A 【文章编号】1007-9572(2010)02-0465-04 Application of Continuous Glucose Monitoring Systen in Improving Glucose Control in T2DM Patients ZHONG Yuan, ZHANG Xiao-yan, HU Ting -jun. Department of Geriatrics, Shanghai NO. 6 Hospital Affiliated to Shanghai Jiaotong Univer- sity,Shanghai 200233,China 【Abstract】 Objective To explore the guiding role of continuous glucose monitoring system(CCMS)in treatment of glucose control in elderly T2DM patients. Methods Two hundred T2DM patients were randomized into groups CGMS and self- monitoring of blood glucose(SMBG). CGMS was performed in group CGMS, 3d, and blood glucose detected in SMBG group. Treatments were adjusted according to glucose monitoring results. All patients wore CGMS for 3 d after 2 weeks. The glucose control was observed, and the fluctuations in blood glucose of CGMS group compared between pre - and post -treatments. Re- sults In CGMS group,serum glycated albumin(GA),mean blood glucose level(MBG),mean amplitude of glycemic excur- sions(MAGE)were(17.0±2.9)%,(7.5±3.2)mmol/L,(3.2±1.0),respectively, significantly lower than in SMBG group〔(18.5±4. 1)%,(9.9±3.0)mmol/L,(5.6±2. 1),respectively 〕. Posttreatment