血必净注射液对多发骨折患者凝血功能影响.pdfVIP

血必净注射液对多发骨折患者凝血功能的影响 徐杰，宋樱花，马明远，潘永，张兴胜，邓梦华，戚振红，张云海 （广东省佛山市中医院ICU，广东 佛山 528000 ） 【摘要】 目的探讨血必净注射液对多发骨折患者凝血功能的影响。方法 将60 例多发骨折患者随机分为血必净治疗组和常规对照组各30 例。对照组给予常规 综合治疗，治疗组在对照组基础上加血必净注射液50ml 静脉滴注，每日2 次， 连续7 天。治疗组和对照组分别在入ICU 后、治疗后第3 天、5 天、7 天抽静脉 血，测血小板计数 （PLT）、凝血酶原时间 （PT）、活化部分酶原时间 （APTT ）、 纤维蛋白原 （Fg）、D-二聚体 （DD ），同时记录两组患者急性生理和慢性健康状 况评分（APACHE II 评分）。结果 治疗组治疗第5、7 天各项凝血检测指标与对 照组有明显差异（P0.05 ），两组APACHE II 评分均较治疗前下降，且治疗7 天 后治疗组较对照组下降明显。结论 血必净注射液能够调节多发骨折患者凝血功 能，改善其高凝状态。 【关键词】血必净注射液；多发骨折；凝血功能；APACHE II 评分 The Effect of Xuebijing Injection on Cruor Function in Multiple Fractures Xu jie,Song ying-hua, Ma mingyuan,Pan yong, Zhang xing-sheng,Deng meng-hua,Qi zhen-hong,Zhang yun-hai. Intensive Care Unit,Foshan Hospital of Traditional Chinese Medicine,Foshan 52800,Guangdong,China 【Abstract 】 Objective To approach the infection o f Xuebijing injection on cruor function in patients with multiple fractures. Methods 60 patients with multiple fractures were randomly divided into treatment group and Xuebijing conventional control group. 30 patients in the control group received the routine treatment, the other 30 patients in the treatment group received the Xuebijing intravenous injection of 60ml, 2 times a day, 7 days additionly.The venous blood was collected to determine the platelet count (PLT), prothrombin time (PT), activated partial zymogen time (APTT), Fibrinogen (Fg), D-dimer (DD) before the therapy and on the 3rd , the 5th and the 7th day after therapy.The APACHE II score were observed before and after therapy. RESULT 5, 7-day treatment group and control group, the detection of targets were significantly different (P 0.05), APACHE II score was lower than those in the two groups before treatment and on the 7th day the treatment group decreased more significantly than the control group. Conclusion Xuebijing injection can regulate