60例小儿中性粒细胞减少症的临床治疗探讨.docVIP

60例小儿中性粒细胞减少症的临床治疗探讨 　　[摘要] 目的 分析小儿中性粒细胞减少症的临床表现和治疗措施。 方法 随机选取该院2013年2月―2014年4月收治的小儿中性粒细胞减少症患儿60例进行临床分析。将60例患儿分为两组，实验组患儿30例，对照组患儿30例。实验组患儿采用常规的抗病毒药物治疗的基础上，使用利可君升白细胞药物进行治疗。对照组患者只应用抗病毒药物治疗。对比两组患儿的治疗有效率，对比两组患儿在治疗前后白细胞的数量和中性粒细胞绝对值的变化。 结果 实验组患者中有25例患者治愈，有效率为83.33%，对照组患者有19例患者痊愈，有效率为63.33%，实验组患者的有效率明显高于对照组，P中国论文网 /6/view-7159685.htm 　　[关键词] 小儿中性粒细胞减少症；小儿疾病；临床治疗 　　[中图分类号] R725 [文献标识码] A [文章编号] 1674-0742（2015）10（a）-0077-03 　　Treatment of Children with Neutropenia Syndrome： An Observation on 38 Cases 　　LUO Chun-long 　　Department of Pediatrics， Jiangdu Maternity and Child Health Care Hospital， Yangzhou， Jiangsu Province， 2225200 China 　　[Abstract] Objective To analyze the clinical manifestations and treatment of children with neutropenia syndrome. Methods A clinical analysis was performed on 60 children with neutropenia syndrome admitted to this hospital from February 2013 and April 2014. They were divided into experimental group and control group with 30 in each one. Patients in the experimental group were treated with leucogen leucocyte-stimulating agents on the basis of conventional antiviral therapy， while those in the control group underwent conventional antiviral therapy singly. The effective rate and changes of number of white blood cells and absolute value of neutrophil before and after treatment were compared between the two groups. Results 25 patients were cured in the experimental group with an effective rate of 83.33%， while 19 were cured in the control group with an effective rate of 63.33%， and the effective rate was higher in the experiment group than in the control group with statistically significant difference， P 　　1.2 方法 　　1.2.1 实验室检查 患儿在入院后，全部进行了血常规的检查，经检查，中性粒细胞绝对值在0.078× 109/L～1.47× 109/L之间，血小板检查无发现明显异常，5例患者伴有轻度的贫血症状，4例患儿出现异性淋巴细胞，5例患儿中性粒细胞中可见中毒颗粒。5例患儿的支原体抗体检测为阳性，6例患儿的C反应蛋白检测为阳性，7例患儿的单纯疱疹病毒抗体检测为阳性。尿常规检查无明显异常。出现腹泻的患儿，经检查发现为消化不良，出现大量脂肪球[2]。 　　1.2.2 一般治疗 为两组患者都进行常规的一般治疗，中性粒细胞减少症患儿的体质和抵抗力不高，因此对真菌和细菌的感染率非常高，因此，患儿居住的环境要每天进行紫外线消毒，督促家属注意患儿的个人卫生，避免细菌接触出现较差感