减重训练及口服二甲双胍对肥胖型多囊卵巢综合征的疗效.docVIP

减重训练及口服二甲双胍对肥胖型多囊卵巢综合征的疗效 　　doi：10.3969/j.issn.1007-614x.2014.20.26 　　摘 要 目的：探讨研究减重训练及口服二甲双胍对肥胖型多囊卵巢综合征的临床疗效并进行安全性分析。方法：2011年1月-2013年12月收治肥胖型多囊卵巢综合征患者80例，并将所有患者随机分为观察组与对照组各40例。其中，对观察组采用单纯进行减重训练治疗，对照组则在观察组治疗基础上再口服二甲双胍辅助治疗。治疗结束后对比分析两组临床治疗效果。结果：①治疗后两组总睾酮、黄体生成素及身体质量指数等指标较之治疗前均有所下降，但对照组总睾酮、黄体生成素的下降程度明显高于观察组。②治疗后两组排卵情况均得到改善，但是对照组排卵率明显高于观察组，且两组数据差异具有统计学意义（P0.05）。结论：减重训练及口服二甲双胍治疗肥胖型多囊卵巢综合征的治疗效果明显高于单纯减重训练，且安全性较好。 　　关键词 减重训练 肥胖型 二甲双胍 多囊卵巢综合征 　　Curative effect of partial weight support and oral metformin on endomorphy type polycystic ovarian syndrome 　　Luo Wei 　　Chuzhou Hospital of Huaian City，Jiangsu 223200 　　Abstract Objective：To explore and study the clinical effects of partial weight support and oral metformin on endomorphy type polycystic ovarian syndrome with safety analysis.Methods：80 cases with endomorphy type polycystic ovarian syndrome were selected from January 2011 to December 2013.All cases were randomly divided into the observation group and the control group with 40 cases in each.Among them，the observation group were treated with simple partial weight support.On the based of the treatment of the observation group，the control group were treated with oral metformin.After treatment，the clinical curative effects of the two groups were contrastively analyzed.Results：①After treatment，the total testosterone，luteinizing hormone and body mass index of patients in the two groups were decreased than those before treatment.The total testosterone，luteinizing hormone of the control group were significantly decreased than those of the observation group.②After treatment，the ovulation of the two groups were improved.The ovulation rate of the control group was significantly higher than that of the observation group.The difference between two groups was statistically significant（P0.05）.Conclusion：The treatment effect of partial weight support and oral metformin in the treatment of endomorphy type polycystic ovarian syndrome is significantly higher than that of the parti