Effects of atorvastatin on essential hypertension with the intervention of paroxysmal atrial fibrillation.docVIP

 PAGE \* MERGEFORMAT 25 Effects of atorvastatin on essential hypertension with the intervention of paroxysmal atrial fibrillation Of: Zhang Rui Hong, Lili Jiang, Wu Huimin [Abstract] Objective To study atorvastatin on essential hypertension with paroxysmal atrial fibrillation (AF intervention. Methods hypertension 79 patients with paroxysmal atrial fibrillation were randomly divided into treatment group (n = 39 and the control group (n = 40). restoration of sinus rhythm group 2 patients after oral administration of aspirin, amiodarone, amlodipine L-acid, the treatment group were treated with atorvastatin 20 mg / d, treatment follow-up of 12 months. observed before and after treatment 2, serum high sensitive C-reactive protein (hs-CRP level, left atrial diameter (LAD changes and recurrence rate of atrial fibrillation. Results After treatment, the treatment group than in the control of serum hs-CRP was significantly lower (P lt;0.01), LAD is less than the control group (P lt;0.01), atrial fibrillation recurrence rate lower than the control group (P lt;0.05). Conclusions long-term use of atorvastatin can reduce the serum levels of hs-CRP, inhibited inflammation, to reduce hypertension in patients with paroxysmal atrial fibrillation recurrence. [Keywords:] atrial fibrillation, hypertension, atorvastatin, high-sensitivity C-reactive protein Abstract: Objective To investigate the intervention effect of atorvastatin on paroxysmal atrial fibrillation in patients with essential hypertension.Methods 79 patients with essential hypertension and paroxysmal atrial fibrillation were randomized into two groups: treatment group (n = 39) and control group (n = 40 ). Patients in both groups received oral administration of aspirin, amiodarone and levamlodipine besylate after returning to sinus rhythm. Atorvastatin 20 mg / d was given in the treatment group. All patients were followed up for 12 months. The changes of serum high-sensitivity C-reaction protein (hs-CRP),