HPLC Determination of Kun Motherwort Stachydrine Hydrochloride Tablets content.docVIP

 PAGE \* MERGEFORMAT 9 HPLC Determination of Kun Motherwort Stachydrine Hydrochloride Tablets content [Abstract] Objective To establish Kun Motherwort Stachydrine Hydrochloride Tablets method for the determination. Methods amino column and acetonitrile - water (volume ratio 78:22) as mobile phase, detection wavelength 202 nm, flow rate was 1 mL * min-1, the column temperature is 30 ℃ . Results Stachydrine Hydrochloride in the 5.625 ~ 28.125 μ g There are a good linear relationship, r = 0.9992, recovery was 100.3%, RSD 2.4%. Conclusion This method is specific, accurate, simple and for Kun Leonurus tablets provide the basis for quality standards. [Keywords:] Kun Motherwort tablets; high-performance liquid chromatography; hydrochloride Stachydrine Kun film is by the author by Motherwort Motherwort Kun cream formulations change derived from the Motherwort, Chuanxiong, peony root, Rehmannia, Chinese angelica and other medicinal composition. Has raised by the transfer of blood, Huayu Health and the new effects, mainly used in clinical Qi stagnation and blood stasis caused by irregular menstruation, menstrual pain, less color dark, postpartum blood stasis net embolism is not achieved satisfactory results. Motherwort is the Fang-jun drug, hydrochloric acid is the active ingredient Stachydrine one of its determination of dissolved salt precipitation method Reye colorimetry [1], UV spectrophotometry [2], TLC [3], HPLC France [4] and so on. In order to better control the quality of the preparation to ensure that the clinical efficacy, this paper, HPLC determination of the content of Stachydrine hydrochloride results show that the method of specific, high precision, separation, and can be used to control the film Hydrochloride Su Kun Motherwort Determination of alkali content. An instrument and reagent WATERS2695-2996-type high-performance liquid chromatography (United States). Kun Motherwort tablets (homemade); hydrochloride Stachydrine reference substance (Lot No