Human papilloma virus infection and esophageal cancer occurred in the path correlation.docVIP

 PAGE \* MERGEFORMAT 10 Human papilloma virus infection and esophageal cancer occurred in the path correlation Author: Shi Xiao-tian Lu Chang-dong Wang Cui Jianguo Chen Ke CAI can Ningtao KE Abstract Introduction Anyang Tumor Hospital and Institute of Clinical Oncology, Peking University, to carry out human papilloma virus (HPV) infection and esophageal cancer-related research subjects occurred in the design ideas, expounded project basis, technical route, the main research content and key and so on. Keywords: esophageal cancer in Anyang of human papilloma virus infection in Since 1998, Peking University School of Clinical Oncology Tumor of the Anyang Tumor Hospital and the union, high incidence of esophageal cancer in Anyang city, the west, through the natural villages, over 35 years old age groups using the traditional net acquisition of esophageal esophageal epithelial cell shedding, and the use of esophageal cancer in Anyang City Tumor Hospital pathological wax block, using PCR and in situ hybridization method from esophageal cancer, esophageal epithelium mild, moderate to severe hyperplasia and normal esophagus exfoliated cells detected HPV16, 18DNA, HPV infection and disease and found that a positive correlation between the degree. In May 2006 began plans to use five years on the high incidence of 10 000 people, HPV infection in human organs to carry out the relevant survey and laboratory work, to explore the human papilloma virus (HPV) infection and esophageal carcinoma relevant. 1 Background Poor prognosis of esophageal cancer is a common malignancy, 5-year survival rate of only about 8%. North Taihang Mountain region is the high incidence of esophageal cancer, esophageal cancer in Anyang in the Taihang Mountains high core areas, annual incidence rate ranks first in the country. 20th century 70s study concluded that dietary factors, lack of protective effect of nutritional factors, intake of excessiv