Nasopharyngeal radiation encephalopathy and the relationship between the radiation field radiation therapy.docVIP

 PAGE \* MERGEFORMAT 21 Nasopharyngeal radiation encephalopathy and the relationship between the radiation field radiation therapy Abstract [Objective] To investigate the nasopharyngeal carcinoma (NPC) after radiation therapy radiation encephalopathy (REP) and radiation therapy the relationship between the radiation field design to seek ways to reduce the incidence of REP. [Methods] Retrospective analysis from 1992 to 2003 of the NPC after radiotherapy REP treated 28 patients, using Varian cadplan accounting for three-dimensional treatment planning system to re-dose of brain lesion. [Results] The whole group of cases the first thing that the site of brain lesions are located in the dose hot spots, the dose by accounting for in excess of 70Gy. [Conclusion] The temporal right to wear the high-dose exposure to wild due to excessive doses of the temporal lobe is the main cause of REP occurred and can be a reasonable ratio of radiation field and the auxiliary temporal wild wild words, such as the nose before the goods in order to reduce the dose of REP than the incidence. 【Key Words】 Nasopharyngeal cancer radiation therapy radiation field radiation encephalopathy Radiation Encephalopathy and Radiotherapeutic Field in Abstract: [Purpose] To investigate the relationship between radiation encephalopathy (REP) after radiation for nasopharyngeal carcinoma (NPC) and radiotherapeutic field design. [Methods] Twenty-eight cases with REP after radiotherapy for NPC from 1992 to 2003 were analyzed retrospectively. The delivery dose of brain injury was recalculated with Varian cadplan treatment planning system. [Results] The initial appearance of brain injury were located in dose hot spots in all the cases, with a dosage exceeding 70Gy. [Conclusions] Overdose of temporal lobe induced by high dose irradiation of temporal bilateral fields is the main cause of REP. Rate of REP can be reduced by adjusting the dose ratio of temporal bilateral fields to sub