Antibacterial and Antioxidant Properties of the Methanolic Extract of the Stem Bark of Pteleopsis hylodendron (Combretaceae)英文文献资料.docVIP
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Antibacterial and Antioxidant Properties of the Methanolic Extract of the Stem Bark of Pteleopsis hylodendron (Combretaceae)英文文献资料
HindawiPublishingCorporation
ChemotherapyResearchandPractice
Volume2011,ArticleID218750,7pages
doi:10.1155/2011/218750
ResearchArticle
AntibacterialandAntioxidantProperties
oftheMethanolicExtractoftheStemBarkof
Pteleopsishylodendron(Combretaceae)
AristideLaurelMokaleKognou,
MartinLutherKoangaMogtomo,
RaymondSimpliceMouokeu, LucieBiyiti,
1
RosalieAnnieNgonoNgane, JulesRogerKuiate,
2 1
AlembertTchindaTiabou,
3
andPaulHenriAmvamZollo
2
1
4
4
1
2
3
LaboratoryofMicrobiologyandAntimicrobialSubstances,UniversityofDschang,P.O.Box67Dschang,Cameroon
DepartmentofBiochemistry,UniversityofDouala,P.O.Box24157Douala,Cameroon
LaboratoryofPhytochemistry,InstituteofMedicalResearchandMedicinalPlantsStudy,
MinistryofScienti?cResearchandInnovation,P.O.Box6163,Yaound′e,Cameroon
DepartmentofBiochemistry,UniversityofYaound′eI,P.O.Box812Yaound′e,Cameroon
4
CorrespondenceshouldbeaddressedtoRosalieAnnieNgonoNgane,angono@
Received27October2010;Accepted17January2011
AcademicEditor:AthanassiosTsakris
Copyright?2011AristideLaurelMokaleKognouetal.ThisisanopenaccessarticledistributedundertheCreativeCommons
AttributionLicense,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkis
properlycited.
Pteleopsishylodendron(Combretaceae)isusedinCameroonandWestAfricafolkmedicineforthetreatmentofvariousmicrobial
infections(measles,chickenpox,andsexuallytransmitteddiseases).Theantibacterialpropertiesofthemethanolicextractand
fractions from stem bark ofPteleopsis hylodendron were tested againstthree Gram-positive bacteria andeight Gram-negative
bacteriausingAgar-welldi?usionandBrothmicrodilutionmethods.Antioxidantactivitiesofthecrudeextractandfractionswere
investigatedbyDPPHradicalscavengingactivityandβ-carotene-linoleicacidassays.Themethanolicextractandsomefractions
exhibitedantibacterialactivitiesthatvariedbetween thebacterialspecies(ID=0.00–25.00mm;MIC =781–12500μg/mLand
0.24–1000μg/mL).Theactivityofthecrudeextractis,however,veryweakcomparedt
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