Spatial patterns of Bovine Corona Virus and Bovine Respiratory Syncytial Virus in the Swedish beef cattle population 英文参考文献.docVIP
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                Spatial patterns of Bovine Corona Virus and Bovine Respiratory Syncytial Virus in the Swedish beef cattle population 英文参考文献
                     
Beaudeau et al. Acta Veterinaria Scandinavica 2010, 52:33
/content/52/1/33
RESEARCH
Open Access
Spatial patterns of Bovine Corona Virus and Bovine Research
Respiratory Syncytial Virus in the Swedish beef 
cattle population
Francois Beaudeau*1,2,3,4, Camilla Bj?rkman4, Stefan Alenius4 and Jenny Fr?ssling5
Abstract
Background: Both bovine coronavirus (BCV) and bovine respiratory syncytial virus (BRSV) infections are currently 
wide-spread in the Swedish dairy cattle population. Surveys of antibody levels in bulk tank milk have shown very high 
nationwide prevalences of both BCV and BRSV, with large variations between regions. In the Swedish beef cattle 
population however, no investigations have yet been performed regarding the prevalence and geographical 
distribution of BCV and BRSV. A cross-sectional serological survey for BCV and BRSV was carried out in Swedish beef 
cattle to explore any geographical patterns of these infections.
Methods: Blood samples were collected from 2,763 animals located in 2,137 herds and analyzed for presence of 
antibodies to BCV and BRSV. Morans I was calculated to assess spatial autocorrelation, and identification of 
geographical cluster was performed using spatial scan statistics.
Results: Animals detected positive to BCV or BRSV were predominately located in the central-western and some 
southern parts of Sweden. Morans I indicated global spatial autocorrelation. BCV and BRSV appeared to be spatially 
related: two areas in southern Sweden (Skaraborg and Sk?ne) had a significantly higher prevalence of BCV (72.5 and 
65.5% respectively); almost the same two areas were identified as being high-prevalence clusters for BRSV (69.2 and 
66.8% respectively). An area in south-east Sweden (Kronoberg-Blekinge) had lower prevalences for both infections 
than expected (23.8 and 20.7% for BCV and BRSV respectively). Another area in middle-west Sweden (V?rmland-
Dalarna) had also a lower prevalence for BRSV (7.9%). Areas with beef herd density  
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