多发性硬化患者表现正常脑白质的纹理分析初探.pdfVIP

中国堕 堡堇 !生塑 鲞箜 期 Chin J Med Imaging TechnoI，2007，VoI 23，No 3 ·453 ． 医学物理与工程学 Elementary texture characteristic analysis of normal appearing white matter in patients with multiple sclerosis NIE Sh“一J㈣ ，TONG Zhong一3，ong ，TONG Long—zheng ，YU Ch“”一shui (1 Biomedi c 0，EnKineerinK ColleKe．Capital Medical LJⅢ1，P，‘sit3，，BeijinK 100069 Chin 2．Depa 。lme?Jl of Radiology，X1La 71It r“Hospita，．CapitⅡ，Medica U” uersit3r．Beijing 1 00053，Ch ，m) ~AbstracQ Objective The run-length matrices were introduced in texture characteristic analysis on microcosmic pathologi— cal changes of normal appearing white matter(NAWM)in patients with multiple sclerosis(MS)．Methods The regions of interest(ROI)were gained from T2WI of 23 patients with MS and 23 normal controls from Xuanwu Hospita1．Then the eig— envectors were obtained from run—length matrices。such as short run emphasis．And the probabilistic neural networks were used 1n classif＼these R()I s．Resulls The COl reC／II~．SS If{I ()f pall(Ills~tIId CODI FOIS、 cr 一8{6。 and ：{- 7 1 (、I|、t I、． ． Conclusion Run length matrices could reflect sorne differences Of t、、tO groups_f1 a certain ex／ellI lrased 01)these images． [Ke)’words~ Multiple sclerosis：Run—length matrices；VChite matter 多发性硬化患者表现正常脑白质的纹理分析初探 聂书君 。童忠勇 童隆正 于春水! (1．首都医科大学生物医学工程学院．北京 100069；2．首都医利大学宣武医院医学影像学部放射手=_}．北京 100053) [摘 要] 目的 利用游程长方法研究多发性硬化表现正常脑白质的纹理特征。方法 列宣武医疏放别科提供的23例 多发性硬化患者和 23名健康志愿者T2WI图像选取感兴趣区．用游程长方法提取短游程因子等参量．然后依据这些特征 参量用概率神经网络对样本分类。结果 患者和健康志愿者分类正确率分别为s4．6 和s3．s 结论 对于率批数据游 程长方法在一定程度上能反映出表现正常脑白质和正常脑白质的不同。 [关键词] 多发性硬化；游程长；脑白质 [中图分类号] R744．51；R445．2 [文献标识码] A [文章编号] 1003—3289(2007)03—0453—03