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乳腺癌超声征象与ER、PR、C-erbB-2表达的相关性研究.pdf
中国医学影像技术2007年第23卷第12期 Chin J Med Imaging Technol,2007,Vol 23,No 12 · 1827·
嚼胸部影像学
Correlation of color Doppler ultrasound morphologic features with the
expression of ER,PR and C-erbB-2 in breast carcinoma
ZENG Hong—yan ’ ,CAO Yong—zheng ,PENG Ge—hong ,TAO Wen—hong ,TANG Wen—tai。
(1.Department of Ultrasound,3.Department of Pathology,Affiliated Hospital of Zunyi Medical College,
Zunyi 563003,China;2.Department of Ultrasound,Huadu District People Hospital,Guangzhou 510800,China)
[Abstract] 0bjective To preliminarily study the correlation between manifestations of breast carcinoma on the color
Doppler ultrasound and the expression of immunohistochemical factors ER,PR,C-erbB-2,and to provide more information
and scientific evidence for the preoperative a~uvant therapy and for the evaluation of the prognosis.Methods Forty-four
patients with breast carcinoma on firmed by histopathology were involved in this study.The color Do ppler ultrasound was
performed in every case before therapy,and ER,PR,C-erbB-2 were performed after operation.The correlation of the color
Do ppler ultrasonographic manifestations of breast carcinoma and the expressions of the three factors were analyzed. Results
①There was not a correlation between the size of breast carcinoma and the expression of ER,PR,C-erbB-2 respectively
(PO.05).②The positive expression rate of ER in spiculated breast carcinoma was higher than non-spiculated(P0.01).
③The positive expression rate of C-erbB-2 was higher in patients with axillary lymph nodes metastasis(P0.05),the posi—
tive expression rate of ER was lower(P0.01).④The positive expression rate of C~erbB-2 was higher in breast carcinoma
tissue of plentiful blood stream than lacking of blood stream (P0.01).Conclusion The manifestations of b
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