脑膜瘤颅外侵及临床及MRI特征探究.docVIP

脑膜瘤颅外侵及临床及MRI特征探究[摘要] 目的：研究脑膜瘤颅外侵及的临床与MRI特征，探讨肿瘤的生长特性。方法：收集1995~2006年我院经手术和病理证实的脑膜瘤颅外侵及13例，并随机抽取相应部位、资料齐全的良性脑膜瘤30例作为对照组(良性脑膜瘤为1993年WHO所界定)，对其临床资料和影像资料进行回顾性分析。观察指标包括脑膜尾征长度、肿瘤基底宽度、肿瘤形态、瘤脑界面、肿瘤大小、肿瘤强化均匀度等。结果：本组脑膜瘤均位于大脑凸面，其脑膜尾征长度、肿瘤基底宽度、肿瘤形态、肿瘤大小与一般良性脑膜瘤相比均有显著差异(P＜0.05)；而瘤脑界面、肿瘤强化均匀度无显著差异(P＞0.05)。脑膜瘤颅外侵及的临床表现也有一定的特性。结论：脑膜瘤颅外侵及有特定的临床和MRI表现。充分认识脑膜瘤颅外侵及的临床与MRI特征，将对其准确诊断与治疗起重要作用。 [关键词] 脑膜瘤；颅外侵及；MRI [中图分类号] R739.45[文献标识码]A [文章编号]1673-7210（2008）09（c）-013-03 Study on the clinical and MRI features of crinial bone penetrative meningioma FENG Shao-ren1, SUN Xi-he2, WANG Bin2, DONG Peng2, CHANG Guang-hui2, YU Ping2 (1.MR Room, the People’s Hospital of Xinyu, Jiangxi Province, Xinyu 338025, China; 2.The Imaging Center, Affiliated Hospital of Weifang Medical College, Weifang 261031, China) [Abstract] Objective: To study the clinical and MRI features of crinial bone penetrative meningioma, and discuss its growth characteristics. Methods: 13 cases of crinial bone penetrative meningioma were confirmed by surgery and histopathology, and 30 cases of the benign meningioma in the corresponding location were selected randomly as the control group (the benign meningioma was defined by WHO in 1993). The corresponding radiological and pathological data were analyzed retrospectively. The observation indexes included the length of dural “tail” sign, the width of tumor basement, tumor shape, tumor-brain interface, tumor size, tumor enhancement uniformity. Results: The crinial bone penetrative meningioma was located in convexity of brain or sphenoidal crest. There were significant differences in the length of “tail” sign, the width of tumor basement, the width of peritumorous edema, the tumor shape and size between the cranial bone penetrative meningioma and the benign meningioma(P 2 结果 2.1 临床表现 位于大脑凸面的脑膜瘤颅外侵及表现为头皮进行性增大的肿块，4例(4/13)有呕吐、抽搐及精神障碍。位于大脑凸面的良性脑膜瘤18例(18/30)有恶心、呕吐及精神障碍，相应部位均未见颅外肿块。两组比较发现，脑膜瘤颅外侵及的颅内压增高症状发生率低于良性脑膜瘤，且前者有颅外局灶症状。 2.2 MRI表现 脑膜瘤颅外侵及与良性脑膜瘤的M