early-life family structure and microbially induced cancer risk早期的家庭结构和微生物诱导癌症的风险.pdfVIP

PLoS MEDICINE Early-Life Family Structure and Microbially Induced Cancer Risk 1,2,3* 4 4 4,5 1 Martin J. Blaser , Abraham Nomura , James Lee , Grant N. Stemmerman , Guillermo I. Perez-Perez 1 Department of Medicine, New York University School of Medicine, New York, New York, United States of America, 2 Department of Microbiology, New York University School of Medicine, New York, New York, United States of America, 3 Veterans Administration Medical Center, New York, New York, United States of America, 4 Kuakini Medical Center and University of Hawaii, Honolulu, Hawaii, United States of America, 5 University of Cincinnati, Cincinnati, Ohio, United States of America Funding: This work was supported A B S T R A C T by NIH grants DK53707 and GM62370, and the Ellison Medical Foundation Senior Scholar in Infectious Diseases Award. The Background funders had no role in study design, data collection and analysis, decision Cancer may follow exposure to an environmental agent after many decades. The bacterium to publish, or preparation of the Helicobacter pylori, known to be acquired early in life, increases risk for gastric adenocarcinoma, manuscript. but other factors are also important. In this study, we considered whether early-life family þ Competing Interests: The authors structure affects the risk of later developing gastric cancer among H. pylori men. have declared that no competing i