阻塞性睡眠呼吸暂停与无症状性反流性食管炎的关系.docVIP

精品论文 参考文献 阻塞性睡眠呼吸暂停与无症状性反流性食管炎的关系 高　敏　邢晓然　刘　红通讯作者 　　中国人民解放军总医院　北京　１００８５３ 　　【摘要】　目的　探索阻塞性睡眠呼吸暂停与无症状性反流性食管炎关系.方法　收集２０１４年６月－２０１５年５月期间行睡眠呼吸监测和电子胃镜的健康体检人群数据,对比有无反流性食管炎者在年龄、体重指数、呼吸暂停低通气指数、平均氧饱和度、最低氧饱和度方面差异.结果　共计入选９９人,单纯呼吸暂停者６７人,呼吸暂停合并反流性食管炎者１９人.呼吸暂停患者反流性食管炎患病比率高于无呼吸暂停者(２２．１％比７．７％,P＜０．０５),有反流性食管炎与无反流性食管炎患者相比:呼吸暂停程度、呼吸暂停低通气指数、最低氧饱和度、平均氧饱和度、体重指数均无统计学差异,反流性食管炎与阻塞性呼吸暂停程度间无明显相关.结论　阻塞性睡眠呼吸暂停可增加反流性食管炎患病风险,反酸烧心等症状不能作为阻塞性睡眠呼吸暂停有无反流性食管炎的主要排除标准.呼吸暂停低通气指数不能作为评估反流风险的唯一指标. 【关键词】　阻塞性睡眠呼吸暂停;无症状;反流性食管炎Therelationshipbetweenobstructivesleepapneaandasymptomaticrefluxesophagitis【Abstract】objective　Toevaluatetherelationshipbetweenasymptomaticrefluxesophagitisandobstructivesleepapnea．Methods　Healthycheck－upcrowdwerecollectedbetweenJune２０１４toMay２０１５．Eelectrongastroscopyandmicromovementsensitivemattresssleepmonitoringsystem wereperformedinpersonswithsnoringbutsourregurgitationorheartburn．Analysisthedifferentofage,BodyMassIndex,Apnea－hypopneaIndex,averageoxygensaturation,minimaloxyＧhemoglobinsaturationbetweenthepatientswithrefluxesophagitisandnon－refluxesophagitispersons．Results　Ninety－ninepersonswereenrolled,amongthemsixty－sevenpersonssufferfrompureObstructivesleepapneaandnineteenwereCombinedwithObstructivesleepapneaandrefluxesophagitis．PatientsofObＧstructivesleepapneahaveamorerisktoillwithrefluxesophagitisthannormalsleepbreathpersons(２２．１％:７．７％,P＜０ ．０５)．However,age,BodyMassIndex,Apnea－hypopneaIndex,averageoxygensaturationandminimaloxyhemoglobinsaturationbetweenthepatientswithrefluxesophagitisandnon－refluxesophagiＧtispersonswerenotstatisticallysignificant．TherelationshipofrefluxesophagitisandtheserveofObstructivesleepapneawerenotfound．Conclusion　Obstructivesleepapneacouldincreasetheriskofrefluxesophagitis．Symptomssuchassourregurgitationandheartburncouldnotbediagnosismethodinthesepeople．ItisinＧappropriatetousetheApnea－hypopneaIndextoassesstheriskofrefluxesophagitis．【Keywords】Obstructivesleepapnea;asymptomatic;refluxesophagitis【中图分类号】R５７１ 【文献标识码】A 　　【文章编号】１００８－６３１５(２０１５)１２－１０９０－０２　　 　　反流性食管炎是一种常见