保胆取石术后口服牛磺熊去氧胆酸预防结石复发临床观察.docVIP

保胆取石术后口服牛磺熊去氧胆酸预防结石复发的临床观察 　　【摘 要】目的：探讨选择性保胆取石术后口服牛磺熊去氧胆酸预防结石复发的临床效果及价值。方法：对本院2015年5月～2017年5月收治的200例符合微创保胆取石术条件的胆囊结石患者为研究对象，随机分为两组，对照组和治疗组，各100例。所有患者在进行手术后保留了功能良好的胆囊，治疗组患者术后给予牛磺熊去氧胆酸进行治疗，对照组除了不给于药物治疗外，其他方面与治疗组相同。观察两组患者临床疗效的差异性。结果：治疗后治疗组患者的胆囊壁厚度以及胆囊收缩功能情况，对比对照组有明显的改善；治疗组患者2年内胆结石复发2例，对照组2年内胆结石复发7例。治疗组患者的复发率为5.00%，明显高于对照组16.00%。组间对比差异具有统计学意义（P0.05）。结论：对保胆取石术后患者给予牛磺熊去氧胆酸进行治疗，具有良好的结果，可有效改善胆囊的收缩功能，提高胆囊壁厚度，大大降低胆囊结石的复发率，且治疗安全性高，极易得到广大患者的接受。因此，值得在临床上大力推广并应用。 　　【关键词】牛磺熊去氧胆酸；复发；保胆取石术 　　Abstract Objective： To explore the clinical effect and value of oral ox-bear deoxycholic acid to prevent the recurrence of calculi.Methods： in our hospital from May 2015 to May 2017， 200 cases of eligible for minimally invasive confirmed gallbladder stone extraction for patients with gallbladder stone as the research object， and randomly divided into two groups， control group and treatment group， 100 cases each.Retained the function after operation was good in all of the patients in the gallbladder， the treatment group patients postoperatively cattle sulfonated bear deoxidation cholic acid treatment， control group except for medical treatment， and other aspects the same as the treatment group.To observe the difference of clinical efficacy between the two groups.Results： the thickness of gallbladder wall and the function of gallbladder contraction in the treatment group were compared with the control group.Two patients in the treatment group had recurrent gallstones in 2 years， and the control group had 7 recurrent gallstones in 2 years.The recurrence rate in the treatment group was 5.00%， significantly higher than that in the control group 16.00%.The difference between groups was statistically significant （P 0.05）.Conclusion： preserved biliary lithotomy postoperative patients given cow sulfonated bear deoxidation cholic acid treatment， with good results， which can effectively improve the gallbladder contraction function， improve the gallbladder wall thickness， greatly reduce the recurrence