不同冷却方法处理后PMMA骨水泥聚合反应特性变化的初步实验研究-介入放射学专业论文.docxVIP

II II 中文摘要 不同冷却方法处理后 PMMA 骨水泥聚合反应特性变化的初步实验研究 结论：将 PMMA 骨水泥置于 0℃冰水混合物中进行急冷处理后，在常温状态下，能 显著延长骨水泥的聚合时间；但到达人体体温后并不延长骨水泥的聚合时间，其聚合 温度及材料力学性能也未受影响。初步结果表明，由于能显著延长骨水泥的聚合时间 而不影响其聚合温度及材料力学性能，故 0℃急冷延长法是一种可行、安全、有效的 方法，值得在临床推广应用。 关键词：PMMA 骨水泥，经皮椎体成形，聚合时间，聚合温度，力学性能 作 者：张 帅 指导老师：倪才方 陈 珑 PAGE PAGE IV 不同冷却方法处理后 PMMA 骨水泥聚合反应特性变化的初步实验研究 英文摘要 An Preliminary Experimental Study in the Change of the Polymerization characteristics of PMMA Bone Cement with Different Cooling Methods Abstract Object: To investigate the polymerization time, polymerization temperature, and mechanical properties of polymethylmethacrylate cement with different hypothermia temperature in Room temperature and 37℃ to evaluate the feasibility, safety and effectiveness during percutaneous vertebroplasty(PVP) with the reduction in temperature. Materials and methods: In this experiment, polymethylmethacrylate cement was used, the powder polymers and liquid monomers were mixed with the Proportion 2:1. The experiments were categorized based on the different types of hypothermic manipulation that were used. In group A(room temperature, sham group), the temperature were kept at 23°C after mixing the bone cement. In group B (precooling the bone cement), the PMMA powder and liquid, as well as the beaker and syringe were stored in the refrigerator (4°C) for 24 hours before mixing. In group C (ice bath cooling), the blend were immediately submerged in ice water after mixing the bone cement at room temperature. Every group was divided into 2 subgroups, for A1, B1 and C1group , the Polymerization was observed in room temperature till the reaction was complete, for A2,B2 and C2,the bone cement was put into 37°C incubator when the paste phase came. There were 7 samples in each group, the polymerization time, polymerization temperature, mechanical properties were observed respectively. The polymerization time Included the time of liquid phase , paste phase and harden phase. The polymerization temperature