慢性肾脏病基础上急性肾损伤透析方法研究.docVIP

慢性肾脏病基础上急性肾损伤透析方法研究 　　[摘要] 目的：探讨慢性肾脏病基础上急性肾损伤的透析治疗方法。方法：将98例慢性肾脏病基础上的急性肾损伤患者随机分为观察者和对照组各49例，观察组采用腹膜透析，对照组采用间歇性血液透析，比较两组透析效果。结果：观察组总有效率为69.4%，对照组总有效率为55.1%，两组临床疗效比较差异有统计学意义（P0.05）；观察组发生透析并发症为8.2%，对照组为16.3%，两组比较差异有统计学意义（P0.05）。结论：腹膜透析作为一种连续性的肾脏替代治疗方式，技术简单、疗效好，且透析相关并发症较少，可作为慢性肾脏病基础上急性肾损伤的主要透析方式。 　　[关键词] 肾脏病；肾损伤；腹膜透析；血液透析 　　[中图分类号] R692 [文献标识码]A[文章编号]1674-4721（2011）07（b）-033-02 　　 　　The research of based on a chronic kidney dialysis of the acute kidney injury methods 　　GONG Xiaoyun 　　The Central Hospital of Yiyang City, Hunan Province, Yiyang 413000, China 　　[Abstract] Objective: To investigate the basis of chronic kidney disease, acute renal injury in dialysis treatment. Methods: 98 cases of chronic kidney disease on the basis of acute kidney injury were randomly divided into the observation and the control group, 49 cases observation group were treated with peritoneal dialysis in the control group were treated with intermittent hemodialysis, dialysis results were compared. Results: The total effective rate was 69.4% in the control group, the total effective rate was 55.1%, Comparison of clinical efficacy was significantly (P0.05); observation group had complications of dialysis was 8.2%, in the control group was 16.3%, the difference was statistically significant (P0.05). Conclusion: Peritoneal dialysis as a continuous renal replacement treatment, the technology is simple and has a good effect, and less dialysis-related complications, as chronic kidney disease, acute kidney injury on the basis of the main dialysis. 　　[Key words] Kidney; Renal damage; Peritoneal dialysis; Hemodialysis 　　 　　慢性肾脏病（CKD）基础上的急性肾损伤（AKI）是临床常见急症，是指患者在原有慢性肾脏病的基础上，由于各种原因所导致的短期内肾小球滤过率迅速下降的一组综合征，是急性肾衰竭的主要原因。2008年1月～2010年6月，笔者对所收治的98例慢性肾脏病基础上的急性肾损伤患者分别采用腹膜透析和间歇性血液透析，现将研究结果报道如下： 　　1 资料与方法 　　1.1 一般资料 　　本组共98例，男58例，女40例，年龄18～82岁，平均54岁；均经临床或肾组织活检证实存在慢性基础肾脏病[1]，其中：慢性肾小球肾炎36例，糖尿病肾病27例，良性小动脉肾硬化症15例，狼疮性肾炎6例，多囊肾5例，慢性间质性肾炎5例，原发性肾病综合征4例；并符合急性肾损伤的诊断标准[2]。将所有患者随机分为观察者和对照组各49例，两组患者在性别、年龄、病程和临床表现等方