早期全静脉营养对低体质量新生儿营养状态及生化指标影响.docVIP

早期全静脉营养对低体质量新生儿营养状态及生化指标影响 　　[摘要] 目的 探讨对低体质量的新生儿试探性采取早期全静脉营养支持治疗的疗效。 方法 选取2013年3月～2014月3月间我院新生儿科收治的150例低体质量新生儿作为研究对象，随机分为观察组（n=75）和对照组（n=75）。对照组给予常规静脉营养治疗，观察组给予全静脉营养治疗，对比两组治疗效果。 结果 治疗后观察组新生儿的平均体重、平均身长和平均上臂围均高于对照组（P0.05）；治疗后观察组新生儿的血清前白蛋白、RBC-C3bRR、RFER的值均高于对照组（P0.05）；尿素氮、肌酐、RFIR的值均低于对照组（P0.05）。 结论 全静脉营养有促进生长发育、增强抵抗力的作用，且不增加肾脏的负荷，适用于低体质量新生儿。 　　[关键词] 全静脉营养；低体质量新生儿；营养状况；生化指标 　　[中图分类号] R723 [文献标识码] B [文章编号] 1673-9701（2014）31-0132-03 　　Effects of early total parenteral nutrition on the nutritional status and biochemical indexes of low-weight newborns 　　ZHANG Jie 　　Department of Pediatric Internal Medicine，Yishui Central Hospital of Linyi City，Linyi 276400，China 　　[Abstract] Objective To investigate effects of early total parenteral nutrition on the nutritional status and biochemical indexes of low-weight newborns. Methods 150 cases of low weight newborn from 2013 March to March 2014 in our hospital were as the object of this study， and were randomly divided into observation group （n=75） and control group（n=75）. The control group was given conventional intravenous nutrition therapy， while observation group was given total parenteral nutrition. Effect of two groups was compared. Results After treatment， the average weight， the average height and the average arm circumference of observation group were higher than that of the control group（P0.05）. After treatment， serum albumin， RBC-C3bRR， RFER values of observation group were higher than that of control group（P0.05）.Urea nitrogen， creatinine， and RFIR values of observation group were lower than that of control group（P0.05）. Conclusion Total intravenous nutrition can promote growth and development， enhance resistance， but do not increase the load of kidney， and is suitable for low weight newborn. 　　[Key words] Total parenteral nutrition；Low weight newborn；Nutritional status；Biochemical indexes 　　由于宫内存活时间缩短，绝大多数早产儿出生时体质量严重偏离正常范围，孕晚期是器官和组织成熟的必要阶段，早产儿由于错失了这一时机，导致多系统的功能体制存在很大的缺陷和不足，不仅继续抑制新生儿宫外的生长发育过程，还给喂养造成了一定的困难。早产儿常因消