早期肠内营养加微生态制剂对重症急性胰腺炎患者疗效影响.docVIP

早期肠内营养加微生态制剂对重症急性胰腺炎患者疗效影响 　　[摘要] 目的 探?早期肠内营养加微生态制剂对重症急性胰腺炎患者疗效的影响。 方法 方便选择2015年1月―2016年5月该院收治的120例SAP进行研究，按随机排列表法分为两组各60例。对照组60例给予肠外营养治疗，观察组60例给予肠内营养联合微生态制剂疗法治疗。治疗2周后，比较2组治疗前后营养相关指标包括血清白蛋白（ALB）和血清前白蛋白（PA）、血红蛋白（Hb）水平；两组治疗前、治疗7、14 d时APACHE Ⅱ评分以及两组多器官功能失调综合征（MODS）与感染发生率。 结果 两组治疗前ALB 、PA、与Hb差异无统计学意义（P0.05）；治疗2周后，两组的上述指标均有所上升，组间比较观察组高于对照组，差异有统计学意义（P0.05），治疗7 d后开始观察组APACHE Ⅱ评分低于对照组，两组7、14 d时的APACHE Ⅱ评分差异有统计学意义（P0.05）；观察组的MODS与感染发生率分别为18.3%、6.7%低于对照组51.7%、31.7%，差异具有统计学意义（P0.05）。结论 对于SAP患者采用早期肠内营养加微生态制剂治疗能更加有效地缓解临床症状，改善患者营养状况，提高临床疗效，值得在临床推广应用。 　　[关键词] 肠内营养；微生态制剂；重症急性胰腺炎；疗效 　　[中图分类号] R21 [文献标识码] A [文章编号] 1674-0742（2017）10（c）-0145-03 　　Effect of Early Enteral Nutrition Plus Microecological Preparation on the Treatment of Patients with Severe Acute Pancreatitis 　　HAI Xiang 　　ICU， Haidian Hospital， the Third Hospital Affiliated to Beijing Medical University， Beijing， 100000 China 　　[Abstract] Objective This paper tries to investigate the effects of early enteral nutrition and probiotics on patients with severe acute pancreatitis. Methods 120 cases of SAP patients from January 2015 to May 2016 in this hospital were convenient selected as the research objects and were randomly divided into the observation group and the control group， with 60 cases in each group. The control group was given parenteral nutrition； the observation group was given enteral nutrition and probiotics therapy. After 2 weeks of treatment， the nutrition related indicators including serum albumin （ALB）and prealbumin （PA）， hemoglobin （Hb）level of the two groups before and after treatment were compared； APACHE II score of two groups and multiple organ function disorder syndrome （MODS）and infection incidence of the two groups before treatment， treatment of 7、 14 d were compared. Results Before treatment， ALB， PA， and Hb showed no significant difference （P0.05）； after 2 weeks of treatment， the indexes of the two groups increased， those in the observation group were higher than the control group， the diff