欣普贝生联合催产素对足月妊娠分娩引产疗效观察.docVIP

欣普贝生联合催产素对足月妊娠分娩引产疗效观察 　　【摘要】 目的：观察欣普贝生联合催产素对足月妊娠引产的临床效果。方法：将在本院足月妊娠引产的140例人员分为三组，分别是欣普贝生1枚塞阴道引产组（60例），小剂量催产素组（40例），欣普贝生联合催产素产组（40例），观察用药后24 h内足月妊娠引产临产时间和足月妊娠引产分娩成功率比较。结果：欣普贝生组足月妊娠引产24 h内临产成功率为53.33%，分娩成功率83.33%；小剂量催产素组分别为30.0%和52.5% ，欣普贝生联合催产素产组分别为70.0%和97.5%，三组两两相比较，差异具有统计学意义（P0.05）。结论：欣普贝生联合催产素用于足月妊娠分娩引产可以缩短临床临产时间和提高成功分娩的几率，效果优于单独使用欣普贝生或者催产素，且用药安全，值得临床使用。 　　【关键词】 欣普贝生； 催产素； 分娩成功 　　Clinical Effect Observation of Dinoprostone Suppositories Combined Oxytocin for Odinopoeia of Full-Term Pregnancy Dilivery/WANG Ying.//Medical Innovation of China，2013，10（15）：064-065 　　【Abstract】 Objective： To observe the clinical effect of dinoprostone suppositories combined oxytocin for odinopoeia of full-term pregnancy delivery. Method： 140 cases were divided into 3 groups as dinoprostone suppositories group， oxytocin group， dinoprostone suppositories combined oxytocin group. Labor time and delivery success rate of all groups after 24 h of medication were observed and compared. Result： Parturient success rate within 24 h and delivery success rate of dinoprostone suppositories group were 53.33% and 83.33%， and oxytocin group were 30% and 52.5%， and dinoprostone suppositories combined oxytocin group were 70% and 97.5%（P0.05）. Conclusion： Dinoprostone suppositories combined oxytocin for odinopoeia of full-term pregnancy delivery can shorten parturient time and increase delivery success rate. It is superior to single use of dinoprostone suppositories or oxytocin and it’s safe， worth of being popularized in clinical work. 　　【Key words】 Dinoprostone Suppositories； Oxytocin； Delivery Success 　　First-author’s address： Yixian People’s Hospital， Yixian 121100， China 　　doi：10.3969/j.issn.1674-4985.2013.15.033 　　现今孕妇选择分娩方式多为阴道分娩，当阴道分娩超过预产期孕妇仍未临产时则需要采用引产的方式，引产已经成为临床上足月妊娠常用方法之一。在孕妇自然临产前，宫颈成熟，抗张能力下降[1]，使得分娩顺利的完成。宫颈成熟是引产一个基本的条件，大部分情况下分娩不能顺利进行是因为宫颈不够成熟。但是在临床上经常可见的一种现象是孕妇宫颈成熟度好，孕周已足月甚至过期妊娠，仍然没有临产的迹象。欣普贝生是一种含前列腺素E2的持续控释栓剂[2]，临床上认为是一种比较安全可靠的促宫颈成熟药物。笔者观察欣普贝生联合催产素在足月妊娠分娩中引产临产时间，引产成功率的临床表现，和单独使用催产