腹腔灌注化疗配合热疗在进展期卵巢癌中疗效分析.docVIP

腹腔灌注化疗配合热疗在进展期卵巢癌中疗效分析 　　[摘要] 目的 对腹腔灌注化疗配合热疗在进展期卵巢癌中的疗效进行研究分析。方法 方便选取该院2016年1月―2017年1月收治的24例进展期卵巢癌患者作为研究对象，将患者随机分为观察组和对照组，其中对照组患者给予紫杉醇静脉注射联合卡铂腹腔灌注治疗，观察组在此基础上给予配合腹部射频热疗治疗，观察对比两组患者的治疗效果。 结果 观察组患者治疗有效率为83.3%，对照组患者治疗有效率为50.0%，且观察组患者总生存期及无进展生存期、不良反应等情况均比对照组好，差异有统计学意义（P0.05）。 结论 紫杉醇镜静脉注射联合卡铂腹腔灌注治疗配合腹部热疗对进展期卵巢癌患者治疗具有较好的作用效果，值得临床推广应用。 　　[关键词] 腹腔灌注化疗；腹部热疗；进展期卵巢癌 　　[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742（2018）02（a）-0052-03 　　Efficacy of Intraperitoneal Perfusion Chemotherapy Combined with Thermotherapy in Advanced Ovarian Cancer 　　YANG Shan-lan 　　Department of Oncology， Dali People’s Hospital， Dali， Yunnan Province， 671000 China 　　[Abstract] Objective This paper tries to study the effect of intraperitoneal chemotherapy combined with thermotherapy in advanced ovarian cancer. Methods 24 cases of advanced ovarian cancer patients in this hospital from January 2016 to January 2017 were convenient selected as the research object， the patients were randomly divided into observation group and control group， the control group was treated with intravenous injection of paclitaxel combined with carboplatin intraperitoneal perfusion therapy， the observation group was given with abdominal radiofrequency hyperthermia therapy， the therapeutic effect of two groups were compared and observed. Results The effective rate of treatment was 83.3% in observation group and 50.0% in control group， and the patients in observation group had better overall survival and progression-free survival than those in control group， with significant difference（P0.05）. Conclusion Paclitaxel intravenous injection combined with intraperitoneal injection of carboplatin with abdominal hyperthermia in patients with advanced ovarian cancer treatment has a good effect， it is worthy of clinical application. 　　[Key words] Intraperitoneal chemotherapy； Abdominal hyperthermia； Advanced ovarian cancer 　　卵巢癌作?榱俅仓谐＜?的恶性肿瘤疾病之一，对患者的生命健康危害十分严重[1]。有研究显示，由于卵巢癌患者早期临床症状不明显，因此，确诊及临床治疗患者时，多处于晚期阶段，治疗方法主要采用手术联合放化疗等治疗，以减少疾病进展对患者的危害，