脑梗死患者血清中ACAhs―CRP和Hcy含量变化关系研究.docVIP

脑梗死患者血清中ACAhs―CRP和Hcy含量变化关系研究 　　[摘要] 目的 探究脑梗死患者血清中ACA、hs-CRP及Hcy的含量变化。 方法 选取该院2012年5月―2014年5月收治的符合标准的脑梗死患者80例；另选正常对照组80例。分别检测其血清中ACA、hs-CRP及Hcy的含量，比较脑梗死组与正常对照组间的差异，并进行检验分析。结果 脑梗死组的ACA、hs-CRP及Hcy水平与正常对照组相比差异有统计学意义（P0.05）；脑梗死组的hs-CRP、ACA与Hcy水平相比较呈正相关性；正常对照组间无相关性。结论 脑梗死患者血清中ACA、hs-CRP及Hcy的含量变化是发生脑梗死的独立危险因素，三项指标联检有利于对脑梗死进行早期诊断与治疗。 　　[关键词] 脑梗死；同型半胱氨酸；ACA；hs-CRP 　　[中图分类号] R74 [文献标识码] A [文章编号] 1674-0742（2015）01（a）-0010-02 　　Study on the Relationship Between the Change of Content of Serum ACA and hs-CRP with That of Hcy in Patients with Cerebral Infarction 　　HU Shikun 　　Clinical Laboratory， Pingdingshan the Second Peoples Hospital， Pingdingshan， Henan Province， 467000， China 　　[Abstract] Objective To explore the changes of content of serum ACA， hs-CRP and Hcy in patients with cerebral infarction. Methods 80 patients with cerebral infarction met the standards of our hospital admitted from May 2012 to May 2014 were selected and other 80 cases were selected as the normal control group. The content of serum ACA， hs-CRP and Hcy was detected in the groups and the results were compared between the two groups and given a check analysis. Results There were significant differences in serum ACA， hs-CRP and Hcy levels between the cerebral infarction group and the normal control group（P0.05）； in the cerebral infarction group， the level of hs-CRP and ACA was positively correlated with that of Hcy； while in the normal control group， the level of hs-CRP and ACA was not correlated with the that of Hcy. Conclusion The content changes of serum ACA， hs-CRP and Hcy in patients with cerebral infarction are independent risk factors of cerebral infarction， and the combined detection of three indexes is conducive to the early diagnosis and treatment of cerebral infarction. 　　[Key words] Cerebral infarction； Homocysteine； ACA； hs-CRP 　　近些年来，随着人们生活水平的提高和工作压力的增多，人们羁患心脑血管疾病的概率逐年增多，特别是脑梗死的发病率，呈加速上升的趋势。目前，临床上对于脑梗死的发病机制尚未完全明确，且缺少创伤性脑梗死早期诊断与治疗的根据[1]。因此，该次研究对2012年5月―2014年5月收治的脑梗死患者的血清抗心磷脂抗体（ACA）、高