阿奇霉素与头孢西丁治疗盆腔支原体感染临床效果对比分析.docVIP

阿奇霉素与头孢西丁治疗盆腔支原体感染临床效果对比分析 　　【摘要】目的：探讨支原体感染盆腔炎患者应用阿奇霉素治疗的临床效果及安全性。方法：按随机数字表法将我院2012年8月至2014年8月收治的140例支原体感染盆腔炎患者分为对照组和观察组，每组70例。两组患者均在给予盆腔炎2号方的同时联合其他药物治疗，其中对照组联合头孢西丁治疗，观察组联合阿奇霉素治疗，比较两组患者的临床疗效和不良反应发生率。结果：观察组痊愈51例，显效11例，有效6例，无效2例，治疗总有效率为9714%；对照组痊愈32例，显效13例，有效12例，无效13例，治疗总有效率为8143%，组间比较差异具有统计学意义（P005）。观察组的子宫血流动力学指标均高于对照组，比较差异具有统计学意义（P005）。观察组的不良反应发生率为714%；对照组为2857%，组间比较差异具有统计学意义（P005）。结论：支原体感染盆腔炎患者应用阿奇霉素治疗的临床疗效较好，不良反应也较少，具有临床推广价值。 　　【关键词】盆腔炎；支原体感染；阿奇霉素；头孢西丁 　　The effect of azithromycin combined cefoxitin in the treatment of pelvic inflammation caused by mycoplasma infectionYANG Xinwei1， TANG Fei 2△. 1. Department of Obstetrics and Gynecology， The 2nd People’s Hospital of Yichang， Hubei 443000， China； 2. Department of Pharmacy， Huangshi Central Hospital， Huangshi 435000， China 　　【Abstract】Objectives： To investigate the clinical effect and safety of azithromycin combined cefoxitin in treating pelvic inflammation patients with mycoplasma infection. Methods： 140 pelvic inflammation patients with mycoplasma infection in our hospital from August 2012 to August 2014 were selected and randomly divided into control group and observation group， 70 cases in each group. Besides the second therapy for pelvic inflammation， the control group jointly received cefoxitin and the observation group received azithromycin for treatment. The clinical efficacy and incidence rate of adverse reaction in the two groups were compared. Results： In the observation group， there were 51 cases cured， 11 cases markedly effective， 6 cases effective， and 2 cases invalid， the total efficiency of treatment being 97.14%； in the control group there were 32 cases cured， 13 cases markedly effective， 12 cases effective and 13 cases invalid， the total efficiency of treatment being 81.43%， with statistically significant differences between the two groups （P005）. The uterine hemodynamics indexes in the observation group were higher than those in the control group， with statistically significant difference （P0