阿帕替尼联合复方苦参注射液治疗恶性肿瘤临床研究.docVIP

阿帕替尼联合复方苦参注射液治疗恶性肿瘤临床研究 　　[摘要]目的 探?采用阿帕替尼联合复方苦参注射液治疗恶性肿瘤的临床效果。方法 选取2017年3～11月我院收治的40例恶性肿瘤患者作为研究对象。按照随机数字表法将其分为两组，每组各20例。对照组患者采用阿帕替尼进行治疗，研究组患者采用阿帕替尼联合复方苦参注射液进行治疗。观察比较两组患者的临床治疗效果、不良反应发生情况、住院费用及住院时间。结果 研究组患者的治疗总有效率（90.00%）高于对照组（55.00%），差异有统计学意义（P0.05）。研究组患者的不良反应总发生率（10.00%）低于对照组（40.00%），差异有统计学意义（P0.05）。研究组患者住院时间为（104.19±22.17）d，短于对照组的（155.37±32.73）d，研究组住院费用为（20 439.35±10 123.13）元，少于对照组的（30 489.17±10 533.71）元，差异有统计学意义（P0.05）。结论 采用阿帕替尼联合复方苦参注射液治疗恶性肿瘤，可以有效减少患者的住院费用，缩短患者住院时间，降低患者不良反应发生率，并能够取得良好的临床效果，具有实用性。 　　[关键词]阿帕替尼；复方苦参注射液；恶性肿瘤 　　[中图分类号] R742.1 [文献标识码] A [文章编号] 1674-4721（2018）4（b）-0130-03 　　Clinical study of Apatinib combined with Compound Kushen Injection in the treatment of malignant tumors 　　ZHONG Hui ZHONG Zhen-wu WU Li-fang ZHONG Yu LIN Zhou-mei 　　Third Department of Internal Medicine，Xingguo People′s Hospital in Ganzhou City，Jiangxi Province，Xingguo 342400，China 　　[Abstract]Objective To investigate the clinical effect of Apatinib combined with Compound Kushen Injection in the treatment of malignant tumors.Methods A total of 40 patients with malignant tumors treated in our hospital from March to November in 2017 were selected as subjects.By the random number table method，all patients were evenly divided into two groups，20 cases in each group.In the control group，Apatinib alone was used，while in the research group，Apatinib combined with Compound Kushen Injection were adopted.The clinical effect，adverse reactions and hospitalization expenses and length of stay were observed and compared between the two groups.Results The total effectiveness rate was 90.00% in the research group，which was higher than that in the control group （55.00%），the difference was statistically significant （P0.05）.The incidence of adverse reactions was 10.00% in the research group，which was lower than that in the control group （40.00%），the difference was statistically significant （P0.05）.The hospital stay in the research group was （104.19±22.17） d，which was shorter than that of the contr