儿童紫癜性肾炎临床与病理关系分析.docVIP

儿童紫癜性肾炎临床与病理关系分析 　　[摘要] 目的 探讨儿童紫癜性肾炎临床与病理的相关性。方法 随机选取2013年3月―2015年7月赤峰学院附属医院儿科收治的100例儿童紫癜性肾炎患儿作为研究的对象，对患儿进行不同临床的分型和病理分析。结果 临床分型中 100例患儿中临床分型以血尿和蛋白尿型患儿最为常见，占40.0%，其次为肾病综合征型，占29.0%。病理分型中以II级为主，占49.0%，其次为III级，占29.0%。尿检正常型患儿以及孤立性血尿或者蛋白型患儿中肾脏病理的损伤程度较轻，血尿和尿蛋白型中II级较多，占62.5%（25/40），III级占17.5%（7/40）。肾病综合征主要以III级为主，占51.7%（15/29）；急进性肾炎型主要以VI级为主。发现临床分型与病理分级之间具有很大的相关性（r=0.392，P0.05）。结论 儿童紫癜性肾炎临床严重程度与病理损伤的程度保持高度的一致性。 　　[关键词] 儿童紫癜性肾炎；临床表现；病理分型 　　[中图分类号] R726.91 [文献标识码] A [文章编号] 1674-0742（2016）09（a）-0020-03 　　[Abstract] Objective To investigate the purpura nephritis in children with pathologic correlation. Methods Randomly selected from March 2013 to July 2015 of 100 children admitted in Chifeng college hospital pediatric children with purpura nephritis as a research object， for children with different clinical classification and pathological analysis. Results Clinical classification in 100 children with clinical classification with hematuria and proteinuria in children is the most common type， accounting for 40.0%， followed by nephrotic syndrome type， accounting for 29.0%. Pathological classification is given priority to with class II， account for 49.0%， followed by level III， accounting for 29.0%. Urine normal type and isolated hematuria or protein in children with type of renal pathology in children with damage to a lesser degree， the class II type is more blood in the urine and urine protein， 62.5% （25/40）， level III accounted for 17.5% （7/40）. Nephrotic syndrome are mainly composed of level III， accounting for 51.7% （15/29）； The accelerated nephritis mainly grade VI. Found that the clinical classification and has a great deal of correlation between pathological grading （r = 0.392， P 0.05）. Conclusion Children purpura nephritis clinical severity and the degree of pathological damage maintain a high level of consistency. 　　[Key words] Purpura nephritis in children； Clinical manifestations； Pathological classification 　　紫癜性肾炎是以IgA沉积于血管壁为特征的小血管炎，在儿童肾病中最为常见，其发病率仅次于急性肾小球肾炎以及