金黄色葡萄球菌院内感染分布的的特点及耐药性分析.docVIP

金黄色葡萄球菌院内感染分布的的特点及耐药性分析 　　【摘要】 目的：分析笔者所在医院临床分离的金黄色葡萄球菌的科室分布及耐药性情况，为临床合理选择抗菌药物提供科学依据。方法：收集2012-2014年住院患者各类标本中分离的金黄色葡萄球菌进行菌种鉴定及药敏试验，回顾性分析医院感染的基本情况。结果：3年内共分离鉴定金黄色葡萄球菌336株，样本分布比例以痰液最高（36.6%），其次是脓液（16.9%），主要科室分布为呼吸内科和ICU。药敏结果显示，金黄色葡萄球菌对万古霉素100%敏感，对青霉素、氨苄西林、红霉素、环丙沙星等多种抗菌药物具有较强的耐药性，耐药率可高达99%以上。结论：金黄色葡萄球菌耐药现象严重，医院应加强对其耐药性监测，根据药敏试验结果合理选用抗生素，以延缓细菌耐药现象的产生。 　　【关键词】 金黄色葡萄球菌； 分布特点； 耐药性 　　中图分类号 R515.9 文献标识码 B 文章编号 1674-6805（2016）19-0068-03 　　Analysis of Nosocomial Infection Distribution and Drug Resistance of Staphylococcus Aureus/HUANG Jian-lin，LUO Yue-qin，LIANG Liang.//Chinese and Foreign Medical Research，2016，14（19）：68-70 　　【Abstract】 Objective：To analyze the distribution characteristics of and drug resistance of Staphylococcus aureus（S.aureus） isolated from various departments in our hospital，and to provide the basis to rationally choose the antibiotics for clinical treatment.Method：The S.aureus isolated from various specimens in our hospital from 2012 to 2014 were selected as the objects，and the species identification and drug susceptibility test were performed，the basic informations of nosocomial infections were retrospective analyzed as well.Result：Totally of 336 strains of S.aureus were isolated in the three years，mainly from the sputum（36.6%） and pus（16.9%），and mainly distributed in the department of respiratory medicine and ICU.The drug susceptibility test showed that all the S.aureus strains were sensitive to Vancomycin but had a high resistance rate（99%） for many antibiotics such as Penicillin、Ampicillin、Erythromycin and Ciprofloxacin.Conclusion：Medical staffs should enhance the resistance detection of S.aureus because of the severity resistance phenomenon，and reasonable choose the antibiotics based on the drug susceptibility test to postponement the resistance phenomenon. 　　【Key words】 Staphylococcus aureus； Distributed character； Drug resistance 　　First-author’s address：Beihai People’s Hospital，Beihai 536000，China 　　doi：10.14033/j.cnki.cfmr.2016.19.035 　　金黄