超声造影在子宫内膜癌肌层浸润中的应用-影像医学与核医学专业论文.docxVIP

PAGE PAGE 10 组与对照组间比较差异有统计学意义（p0.01）。增强时间、有无粗大血管在实验 组中肌层浸润与无肌层浸润组间比较差异有统计学意义（p0.01）。实验组浅肌层 浸润与深肌层浸润组在增强水平方面比较差异有统计学意义（p0.01）。3、超声造 影参数中峰值强度在实验组病灶与其周围肌层间比较差异有统计学意义（p0.01）； 始增时间、达峰时间、峰值强度、增强速率及半廓清时间在实验组与对照组间比 较差异有统计学意义（p0.05）。 结论：1、超声造影对临床术前判断子宫内膜癌肌层浸润程度有一定的指导意义。 2、超声造影有助于提高术前子宫内膜癌诊断及分期诊断。 关键词：子宫内膜癌；超声造影；超声造影剂；肌层浸润 Application of Contrast-enhanced Ultrasound in the myometrial invasion of endometrial carcinoma Abstract Objective: To investigate the potential usefulness of contrast-enhanced ultrasound in the preoperative evaluation endometrial carcinoma and summarize its characteristics of enhancement pattern and time-intensity curve. Methods: we choose 28 patients with endometrial carcinoma that were confirmed by pathological examination after diagnostic curettage and 6 women who had normal endometria as a control group in the First Affiliated Hospital, Bengbu Medical College. All the Patients underwent real-time gray scale contrast-enhanced ultrasound examination with SonoVue, using pulse inversion harmonics. The equipment used in the study was a Philips IU22 ultrasound machine with 2~5MHz abdomina transducer. Contrast General imaging mode was used for post contrast scanning. After examinations, compare the differences of the contrast-enhanced patterns of all patients. The perfusion process of lesions observed and sonographic characteristics of the masses were analyzed. Then started QLAB software to analysis all images, to draw Time-Intensity curves(TIC), to obtain the shapes of curves and contrast parameters: baseline intensity, peak intensity, relative rise in intensity, arrival time, time to peak, enhancement time, rising rate and half wash-out time. Obtain the results of the diagnosis of myometrial invasion of endometrial carcinoma by preoperative contrast-enhanced ultrasound, intraoperative gross visual inspection and compare the results with postoperative pathological examination results. Comparing with the pathological results，we analyzed shapes of cu