超微血管成像(SMI)技术和超声造影(CEUS)技术评价不同 厚度颈动脉斑块内新生血管的对比研究-影像医学与核医学专业论文.docxVIP

万方数据 万方数据 目 录 中文摘要 ·········································································· 1 英文摘要 ·········································································· 4 英文缩写 ·········································································· 7 研究论文 超微血管成像(SMI)技术及超声造影(CEUS)技术评价 不同厚度颈动脉斑块内新生血管的对比研究 前言 ·········································································· 8 材料与方法 ································································· 9 结果 ········································································ 12 附图 ········································································ 13 附表 ········································································ 17 讨论 ········································································ 19 结论 ········································································ 25 参考文献 ·································································· 26 综述 关于颈动脉粥样硬化斑块的影像学研究 ························ 31 致谢 ·············································································· 43 个人简历 ········································································ 44 中 中 文 摘 要 PAGE 1万方数据 PAGE 1 万方数据 超微血管成像(SMI)技术和超声造影(CEUS)技术评价不同厚度颈 动脉斑块内新生血管的对比研究 摘 要 目的：应用超微血管成像(Superb microvascular imaging，SMI)技术及 超声造影(Contrast enhanced ultrasound，CEUS)技术检测颈动脉粥样硬化 斑块内的新生血管，比较不同厚度的颈动脉粥样硬化斑块内新生血管的差 异。并且对比研究超微血管成像(SMI)技术与超声造影(CEUS)技术检测颈 动脉粥样硬化斑块内新生血管是否具有一致性。 方法： 选择2014年7月至2015年12月在我院经常规二维超声及多普勒超声确 诊存在低回声、等回声的颈动脉粥样硬化斑块患者56例(共计80个斑块)， 其中男40例，女16例，年龄41~84岁,平均(64.1±8.2)岁，性别、年龄差 异无统计学意义，患者均签署造影检查知情同意书。 按照斑块厚度分为三组：斑块厚度1.5mm~2.4mm组，共24例；斑块 厚度2.5mm~3.4mm组，共28例；斑块厚度≥3.5mm组，共28例。对所有 入选患者首先进行常规超声检查，观察斑块位置、回声、大小、形态，并 测量颈动脉粥样硬化斑块最厚处，在此切面应用超微血管成像(SMI)技术 检测斑块内的增强情况(即低速血流显像)，然后应用超声造影(CEUS)技术 检测此最厚切面处的斑块内增强情况。观察并记录斑块内超微血管成像 (SMI)技术增强情况以及超声造影(CEUS)技术增强情况，按照分级标准进 行分级，统计数据。 应用SPSS17.0统计软件，分别对超微血管成像(SMI)技术及超声造影 (CEUS)技术增强分级结果的双向有序分级资料应用Spearman秩相关检 验，以等级相关系数rs值为正表示正相关，rs值为负表示负相关，rs值等于 零表示零相关，rs是总体等级相关系数ρs的估计值；对超微血管成像(SMI)