骶髂关节磁共振扫描对强直性脊柱炎诊断价值-影像医学与核医学专业论文.docxVIP

上海交通大学医学院同等学力硕士研究生论文 上海交通大学医学院同等学力硕士研究生论文 PAGE PAGE 10 BASDAI 评分与晨僵时间呈正相关(rs=0.335，P0.05)，ESR 和 CRP 间呈 正相关 (rs=0.510，P0.05)。在 P=0.05 水平，其余指标间相关性无统计 学意义。 结论 在强直性脊柱炎骶髂关节改变中, 骨髓水肿程度与 BASDAI 评分、晨僵时间呈正相关，骨髓水肿程度与 ESR 和 CRP 无明显相关性。 骨髓水肿程度的 SPARCC 评分可作为判定强直性脊柱炎活动性的依据之 一。 关键词 骶髂关节炎，磁共振成像，强直性脊柱炎，弥散加权成像， 骨髓水肿，相关性 VALUE OF MRI IN THE DETECTION OF SACROILIITIS FOR ANKYLOSING SPONDYLITIS ABSTRACT CHAPTER1 VALUE OF MRI IN THE DETECTION OF SACROILIITIS FOR ANKYLOSING SPONDYLITIS Objective To investigate the value of varialble signs of MRI in diagnosing the sacroiliitis in ankylosing spondylitis(AS), compare CT and MRI signs, provide valuable reference for clinical diagnosis. Methods According to the modified NEW YORK criteria for AS, basing on clinical data and CT examination of sacroiliac joints(SIJs), 78 patients were diagnosed AS. They were detected with CT and MRI of the sacroiliac joints within a week respectively. 25 volunteers were examinated with MRI as the control group. Fast spin echo T1-weighted imaging(FSE-T1WI), fast spin echo T2-weighted imaging(FSE-T2WI), fat saturated-FSE-T2WI (FS-FSE-T2WI), diffusion weighted imaging(single short-echo planar imaging,SS-EPI), and three dimensional fast spoiled gradient-recalled (3DFSPGR) sequences were performed in oblique coronal planar. MRI images of two groups were compared, MRI signs of sacroiliitis in AS were summed up. Comparative analysis of some signs between CT and MRI was done in the experimental group. Results First, compared with the control group, MRI signs of AS on SIJs are as follows: cartilage and joint cavity abnormality(n=69), bone erosion (n=63), sclerosis(n=47), bone marrow edema(n=33), signal abnormality showed on DWI(n=36) and fat deposition in bone marrow(n=14). Second, Comparative analysis in lesion group showed that MRI is superior to CT in displaying different sacroiliac lesions except sclerosis. Conclusion MRI is very valuable in dectecting sacroiliitis in AS. Much abnormality which CT