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Notes for Guideline Not recommend sole application of aspirin for VTE prevention Close observation of complications, timely diagnosis and treatment if severe bleeding tendency appears Not recommend combination of pharmaceutical products, because of the increased possibility of bleeding Thank you! (1) congestive heart failure, lung edema, or severe leg edema; (2) lower extremity deep venous thrombosis, thrombosis phlebitis, or pulmonary embolism; (3) intermittent pneumatic compression devices and graduated compression stockings could not apply due to local abnormalities in the leg (such as dermatitis, gangrene, recent skin graft surgery), severe atherosclerosis of lower extremity vascular or other ischemic vascular disease, leg severe deformity. China Guideline for Venous Thromboembolism Prevention after Major Orthopedic Surgery DVT - PTE A concept needs comprehensive understanding Venous thromboembolism,VTE Deep venous thrombosis,DVT Pulmonary thromboembolism,PTE VTE = DVT + PTE DVT and PTE , two clinical forms of the same disease at different stages and different sites High incidence of VTE after major orthopaedic surgery- extremely high-risk population of VTE with a 20-year routine prevetion history in aboard operation DVT (%) PE (%) Total incidence Proximal incidence Total incidence Fatal incidence% THR 42-57 18-36 0.9-28 0.1-2.0 TKR 41-85 5-22 1.5-10 0.1-1.7 Hip fracture 46-60 23-30 3-11 0.3-7.5 Incidence of DVT after Major Orthopedic Surgery in Asian Countries 02-07~03-03 19 centers in Asia , 407 patients THR:175 patients(43.0%) TKR:136 patients(33.4%) Hip fracture: 96 patients(23.6%) 278 patients(68.3%)underwent angiography Centers included China:Peking Union Medical College Hospital, Beijing People’ s Hospital, Sixth Peoples Hospital of Shanghai Jiao Tong University Chinese Taiwan, Korea, Malaysia, Philippines, Indonesia and Thailand Results: 120 patients (43.2%) developed DVT A
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