空气污染与肺部健康-临床医学专业论文.docxVIP

本研究发现急性组的N02、CO浓度均值，慢性组中的CO浓度均值与肺功能 本研究发现急性组的N02、CO浓度均值，慢性组中的CO浓度均值与肺功能 具有显著性负相关。另一方面，无论是在急性还是慢性维度，污染物浓度在小时水 平的离散度指标，尤其是变异系数，与肺功能存在广泛且显著的负相关。而且其关 联在不同分组、不同污染物间的一致性明显好于污染物浓度均值与肺功能关联的结 果。该结论对于未来指导防治空气污染导致的健康损害具有重要意义。 关键词：空气污染；肺功能；相关性； 变异系数 万方数据 Part Part 1 Relationship Between Air Pollution and Lung Function：New Exposure Assessment Indicator Abstract objective： The aim was to explore the relationship between air pollution and lung function in China，which has significantly high air pollution level．Simultaneously，we tried to find ifthe air pollutants concentration’S scatter degree can be used as a predictor of the influence of air pollution exposure on lung function． Method： We matched demographic data and lung function data frOm the China National Health Survey(cNHs)wh ich was the National Science＆Technology Pillar Program during the 1 2th Five-year Plan Period with air pollution data from National Air Pollution Monitoring Network．We utilized multiple linear regression to adjust gender，age，height，weight and pulmonary disease，and explore the relationship between air pollution and lung function in both acute and chronic dimension． Result： In chronic group，standard deviation of nitrogen dioxide(N02)，ozone(03)and coefficient of variation of constituent particles of particulate matter which is less than 2．5 pm in diameter(PM2．5)，constituent particles of particulate matter which is less than 1 0 Ijm in diameter(PMl0)，sulfur dioxide(S02)，N02，Air Quality Index (AQI)had significantly negative correlations with forced vital capacity(FVC)．Mean value of carbon monoxide(CO)and standard deviation of N02，03，CO and coefficient of variation of PM2．5，PMlo，S02，AQI had significantly negative correlations with forced expiratory volume in 1 second(FEVl)．Mean value of PM2．5， PMl0，SOz，N02．CO，AQI，standard deviation ofAQI，coe怖cient of variation of 03 had significantly negative correlations with FEVI／FVC．Its worth noting that mean value of PM2．5，PMl0，S02，N02，AQI had positive correlations with