老年高血压患者脑血流动力学的变化特征.docVIP

老年高血压患者脑血流动力学的变化特征 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：老年高血压患者脑血流动力学的变化特征 1 1 对象与方法 2 2 结 果 3 3 讨 论 4 文2：彩色多普勒超声对窒息新生儿脑血流动力学的检 5 1 对象和方法 5 2 结果 6 3 讨论 6 参考文摘引言： 7 原创性声明（模板） 8 文章致谢（模板） 9 正文 老年高血压患者脑血流动力学的变化特征 文1：老年高血压患者脑血流动力学的变化特征 【Abstract】 Objective To probe into the influence of hyperteion history to cerebrovascular hemodynamic paramete in elderly. Methods 2 321 individuals aged 65～80 year were selected from a cohort. Participants were divided into 2 groups according to hyperteion history in baseline. 1 168 cases with history of hyperteion were defined as hyperteion case group and 1 153 cases without history of hyperteion were defined as control group. Differences and distribution of cerebrovascular hemodynamic paramete between 2 groups were compared. Results The cerebrovascular hemodynamic paramete synthesized scores in case and control groups were ± and ±(P). The abnormal rates of the score(75 points) in 2 groups were % and %(P). Kinematic paramete in case group were significantly lower than those in control group. However, dynamic paramete as well as exposure rates of history of heart disease, obese and family history of stroke in case group were significantly higher than those in control group (P). Conclusio There is significant influence of hyperteion history to cerebrovascular hemodynamic in elderly and it may increase the risk of stroke. 【Key words】 Hyperteion; Hemodynamic; Stroke 研究表明，血压水平与脑血管血流动力学参数(cerebrovascular hemodynamic paramete，CVHP)的异常变化密切相关〔1，2〕，高血压患者出现CVHP异常变化可能进一步增加卒中风险〔3〕。老年人是高血压的主要患病群体，也是脑卒中发病的主要人群，但有关老年人高血压与CVHP的关系尚未见报道。为了探讨老年人高血压病史对CVHP的影响，为卒中风险评估提供可靠的依据，本研究对上海市 农村 社区卒中危险因素队列研究人群中年龄65～80岁老年人的基线调查资料进行 总结 和分析。 1 对象与方法 对象 整群抽取上海市某农村社区≥40岁卒中危险因素队列研究人群，选择年龄65～80岁者作为研究对象，共计2 321例，其中有高血压病史者为病例组，无高血压者为对照组。血压水平的定义与分类参照2004年《 中国 高血压防治指南》规定〔4〕(血压平均值收缩压≥140 mmHg和(或)舒张压≥90 mmHg，或正在服用降压药者确诊为高血压患者)，其他危险因素的定义同本队列人群的基线调查资料〔5〕。病例组1 168例，男453例，女715例，平均年龄(±)岁;对照组1 153例，男455例，女698例，平均年龄(±)岁。两组平均年龄和性别分布无统计学差异，具有可比性。 方法 自行设计