浅谈原发性高血压患者血清C型利钠肽的变化及临床意义（行业资料）.doc

浅谈原发性高血压患者血清C型利钠肽的变化及临床意义（行业资料） 文档信息 ： 文档作为关于“行业资料”中“医学资料”的参考范文，为解决如何写好实用应用文、正确编写文案格式、内容素材摘取等相关工作提供支持。正文4608字，doc格式，可编辑。质优实惠，欢迎下载！ 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：浅谈原发性高血压患者血清C型利钠肽的变化及临床意义 2 1 材料与方法 3 2 结果 3 3 讨论 4 文2：慢性肺源性心脏病患者血清脑钠肽水平变化及临床意义 5 1 资料与方法 5 2 结果 6 3 讨论 6 4 参考文献 7 参考文摘引言： 7 原创性声明（模板） 7 文章致谢（模板） 8 正文 浅谈原发性高血压患者血清C型利钠肽的变化及临床意义（行业资料） 文1：浅谈原发性高血压患者血清C型利钠肽的变化及临床意义 Change of serum C-type natriuretic peptide level in patients with essential hyperteion GUO Chang-l，LI of Cardiology，The Fit Affiliated Hospital of Xinxiang Medical College，Henan 453100，China 【Abstract】 Objective To explore the change of serum level of C-type natriuretic peptide in patients with essential hyperteion and to evaluate the relatiohip between the serum level of C-type natriuretic peptide and stage of hyperteion as well as target organ injury. Methods The serum level of C-type natriuretic peptide were determined with radioimmunossay in 97 EH patients and 50 controls. Results The serum levels of C-type natriuretic peptide in EH patients were significantly higher than those in controls. The serum levels of C-type natriuretic peptide increased gradually fromgrade 1 to grade 3 EH. The serum levels of C-type natriuretic peptide in patients with renal and/or cardio and/or cerebral vascular complicatio were significantly higher than those in patients without differences were significant，. Conclusion The serum level of C-type natriuretic peptide in EH patients were closely related to the severity of EH process and target organ injuries. 【Key words】 Essential hyperteion;C-type natriuretic peptide;Radioimmunossay DOI:/  本文对97例原发性高血压患者的血清CNP水平进行检测，以探讨血清CNP与高血压分期及并发症的关系。 1 材料与方法 一般资料 选取我院2008年10月至2010年4月收治的97例初诊为原发性高血压患者作为高血压组，诊断标准见2005年《中国高血压防治指南》，排除冠心病、心肌炎、高血脂、肝肾功能不全、2月内服用他汀类药物等。其中男58例，女39例，年龄31～69岁。其中1级高血压31例，2级高血压32例，3级高血压(伴心脑肾并发症)34例。对照组为同期门诊体检合格的50例健康者，男27例，女23例，年龄30～64岁。 方法 取抗凝外周血3 ml，采用放射免疫分析血清CNP水平。CNP RIA kit由解放军总医院放免所提供。其批内变异系数10%，批间变异