苗药血脉通胶囊对单纯型糖尿病视网膜病变患者视网膜功能的影响.docVIP

· 2461 · · 中 医 · 中 西 医 结 合 研 究 · 苗药血脉通胶囊对单纯型糖尿病视网膜病变患者 视网膜功能的影响 任平均，冯玉明，庞朝善 【摘要】 目的 观察苗药血脉通胶囊对单纯型糖尿病视网膜病变眼底荧光血管造影 (FFA) 、 视野平均敏感度、 视网膜电图震荡电位 (ERG-OPs) 的影响。方法 将确诊为气阴两虚、瘀血阻络证单纯型糖尿病视网膜病变患者94 例(188只眼)随机分为治疗组及对照组，分别给予苗药血脉通胶囊及羟苯磺酸钙胶囊，并同时口服自制三七粉胶囊 治疗，连续用药3个月。观察治疗前后FFA 和视野平均敏感度、 ERG-OPs 的变化。结果 治疗组疗效优于对照组 (P 0.01);治疗组和对照组视野平均敏感度比较，差异有统计学意义 (P0.001); 治疗组 OPs O1峰潜伏期较治疗前 缩短 (P0.001)。 结论 苗药血脉通胶囊可改善单纯型糖尿病视网膜病变的眼底情况，提高视野平均敏感度，对 ERG-OPs 也有一定的作用，使视网膜血流情况稳定，是防治早期糖尿病视网膜病变的有效药物。 【关键词】 糖尿病视网膜病变；荧光素血管造影术 【中图分类号】 R587.26 【文献标识码】 A 【文章编号】1007-9572(2011)07-2461-03 Ef fects of Miao Medicine Xuemaitong Capsule on Retinal Functioning among Simple Diabetic Retinopathy Patients REN Ping-jun,FENG Yu-ming,PANG Chao-shan. Depatment of TCM, Xingtai Peoples Hospial,Xingtai 054001,China 【Abstract] Objective To observe the effects of Miao medicine Xuemaitong capsule on the Fundus Fluoreseseei angiog- raphy(FFA),mean sensitivity(MS),and Electroretinogram - Oscillatory Potentials(ERG-OPs) of simple diabetic retinopa- thy patients. Methods Ninety -four patients(188 eyes) with diabetic retinopathy who were diagnosed with qi and Yin deficien- cy and blood stasis resistance were randomly divided into the observation group and the control group. treated with Xuemaitong capsules and dobesilate calsium capsules respectively in addition to homemade oral Sanqi(panax notoginseng) powder capsules for both groups. Both treatment regimens lasted for 3 months. FFA,MS, and ERG - OPs were observed for both groups before and after treatment. Results The experimental group showed a curative effect superior to that of the control group(P0.001); MS showed significant differences between the observation group and the control group (P0.001); the incubation period of OPs O, peak was shortened in the observation group(P0.001). Conclusion Xuemaitong capsule is an effective drug for ear- ly diabetic retinopathy which improves the conditions of the fundus oculi as well as the M