Mal-PEG2-Val-Arg-PABC-OMe-Eribulin-生命科学试剂-MCE.pdfVIP

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Mal-PEG2-Val-Arg-PABC-OMe-Eribulin

Cat.No.:HY-177953

CASNo.:2676196-79-3

分⼦式:C₇₁H₁₀₁N₇O₂₁

分⼦量:1388.6

作⽤靶点:Drug-LinkerConjugatesforADC;c-Met/HGFR

作⽤通路:Antibody-drugConjugate/ADCRelated;ProteinTyrosine

Kinase/RTK

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Mal-PEG2-Val-Arg-PABC-OMe-Eribulin(CompoundL-1)是⼀种药物-连接⼦偶联物，由O-MeEribulin(HY-

159576)和连接物Mal-PEG2-Val-Cit-PAB-OH(HY-130222)组成。Mal-PEG2-Val-Arg-PABC-OMe-Eribulin可

⽤于合成抗HER3/MET抗体药物偶联物(ADC)[1]。

REFERENCES

[1].Li,etal.Her3/metbindingmoleculeandpharmaceuticalusethereof.WO2025056029A1.WIPO(PCT).2024-09-13.

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