曲美他嗪联合瑞舒伐他汀治疗老年冠心病不稳定型心绞痛临床观察.docVIP

曲美他嗪联合瑞舒伐他汀治疗老年冠心病不稳定型心绞痛临床观察 　　doi：10.3969/j.issn.1007-614x.2014.20.4 　　摘 要 目的：研究曲美他嗪联合瑞舒伐他汀治疗老年冠心病不稳定型心绞痛的临床疗效。方法：2012年1月-2013年7月收治老年冠心病不稳定型心绞痛患者90例，分成3组，对照组①为常规治疗，对照组②在常规基础上加曲美他嗪治疗，试验组选用曲美他嗪联合瑞舒伐他汀治疗，均连续用药2个月后进行各项指标检查并作相关记录，对比3组临床疗效。结果：试验组相比于2个对照组，用药后各项临床指标有了明显改善，心绞痛持续时间、心绞痛发作频率均有所减少，心绞痛剧烈程度略有降低，心电图异常比例减少，有效率显著提高。对照组②的疗效比对照组①略好，又逊于试验组。结论：曲美他嗪联合瑞舒伐他汀可用于老年冠心病不稳定型心绞痛的治疗，效果更好，值得推广。 　　关键词 曲美他嗪 瑞舒伐他汀 冠心病 不稳定型心绞痛 　　Clinical observation of trimetazidine combined with rosuvastatin in the treatment of senile coronary heart disease unstable angina pectoris 　　Zhang Lu 　　The Peoples Hospital of Tacheng District，Xinjiang 834700 　　Abstract Objective：To study the clinical effect of trimetazidine combined with rosuvastatin in the treatment of senile coronary heart disease unstable angina.Methods：90 cases with senile coronary heart disease unstable angina were selected from January 2012 to July 2013.They were divided into 3 groups.The ① control group were treated with conventional treatment.The ② control group were treated with trimetazidine on the basis of conventional.The experimental group were treated with trimetazidine combined with rosuvastatin.3 groups were treated for 2 months.The indicators were checked and given related record.The clinical curative effect of 3 groups were compared.Results：The experimental group compared with two control group，the clinical indicators were improved obviously after treatment.The duration of angina pectoris and the frequency of angina pectoris attack were all decreased.The angina pectoris intensity was slightly reduced.The proportion of abnormal ECG was decreased.The effective rate was significantly improved.The curative effect of the ② control group was slightly better than that of the ① control group，and was inferior than that of the experimental group.Conclusion：Trimetazidine combined with rosuvastatin can be used for the treatment of senile coronary heart disease unstable angina.Its effect is better，so it is worthy of promotio