Salvia delayed Hyperhomocysteinemia high atherosclerotic rabbits Morphological study.docVIP

 PAGE \* MERGEFORMAT 9 Salvia delayed Hyperhomocysteinemia high atherosclerotic rabbits Morphological study Of: Zhouling Sheng, Zhang Haiyan, Zhou Road, Tanzania [Abstract] Objective To study the Salvia on high homocysteine #8203;#8203;(Hhcy) rabbit atherosclerotic intervention. Methods 40 rabbits were randomly divided into control group (A), methionine group (B), high-fat group (C), SM + Met group (D), were detected in experiments 0,4,8 weeks, plasma homocysteine #8203;#8203;(Hcy) and pathological changes in abdominal aortic vascular pathology observed. Results B Group 4 8 weeks, plasma Hcy was significantly higher than the same time segment A group (P lt;0.01); D group and B group, the level of close to 4 weeks, 8 weeks was lower than the same time segment B group (P lt;0.01). Help with medication prolonged plasma Hcy SM content increased the intervention group was significantly less than its time rate of methionine group. pathologic changes: B group, C group there was general observation of abdominal aortic plaque formation; D group and no significant difference between the normal group . Conclusion HHcy can induce the formation of atherosclerosis, Salvia has a delay or interfere with the formation of atherosclerotic effect. [Keywords:] Atherosclerosis; Salvia; high homocysteine The high L-methionine were used Hhcy hyperlipidemia rabbit model of high fat diet and hyperlipidemia rabbit model with the control group, the formation of SM + Met group comparison of arterial plaque, and the same type of plasma cysteine #8203;#8203;(Hcy) levels in comparison to observe the formation mechanism of AS caused Hhcy; inspection of Danshen on Hhcy AS pathological process caused by intervention, as Hhcy prevention, delay or control the formation of AS, reduce heart disease, cerebrovascular disease incidence Risk expand new ideas and provide new targets. 1 Materials and equipment 1.1 Animal Shaixuan 40 male rabbits of China (Wuhan Wanqian by the experimenta