Calcaneal BMD Obtained by Dual X-Ray and Laser Predicts Future Hip Fractures—A Prospective Study on 4？398 Swedish Women英文文献资料.docVIP

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Calcaneal BMD Obtained by Dual X-Ray and Laser Predicts Future Hip Fractures—A Prospective Study on 4？398 Swedish Women英文文献资料.doc

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Calcaneal BMD Obtained by Dual X-Ray and Laser Predicts Future Hip Fractures—A Prospective Study on 4？398 Swedish Women英文文献资料

SAGE-HindawiAccesstoResearch JournalofOsteoporosis Volume2010,ArticleID875647,6pages doi:10.4061/2010/875647 ResearchArticle CalcanealBMDObtainedbyDualX-RayandLaser PredictsFutureHipFractures—AProspectiveStudyon 4398SwedishWomen TorkelB.Brismar, ImreJanszky, 1 2andL.I.M.Toft1,3,4 1 DivisionofRadiology,DepartmentforClinicalScience,InterventionandTechnology,KarolinskaInstitute, KarolinskaUniversityHospital,Huddinge,14186Stockholm,Sweden DivisionofPublicHealthEpidemiology,DepartmentforPublicHealthSciences,KarolinskaInstitute,17177Stockholm,Sweden MerckSharpDohme,19278Sollentuna,Sweden 2 3 4 P?zerAB,Stockholm,19190Sollentuna,Sweden CorrespondenceshouldbeaddressedtoTorkelB.Brismar,torkel.brismar@ Received22October2009;Revised8March2010;Accepted15March2010 AcademicEditor:RogerPrice Copyright?2010TorkelB.Brismaretal. This is an open access article distributed under the Creative Commons Attribution License,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperly cited. The predictive value of dual X-ray and laser (DXL) calcaneal BMD (BMDDXL) on hip fractures was prospectively studied in 4,398femalesaged55to99years.Theaveragefollow-upperiodwas3yearsand11monthswithatotalof17,270personyears. Fractureswereidenti?edfromthenationalpatientregister.Afterinclusion,130femalessustainedahipfracture.Theageadjusted hazardratioforT-score ?2.5versus ?2.5was2.64.Ofallpatientswhosustainedahipfracture78%hadaT-scoreof?2.5 orbelow.Theannualhipfractureratewas0.26%atT-scores ≥ ?2,but1.5%atT-scores ≤ ?2.5.Theareaundercurvefor themodel including calcaneal BMD , follow-up time, and age to prospectively predict hipfractureswas 0.84. Conclusions. DXL CalcanealBMDDXLobtainedbyDXLCalscanpredictshipfracturesandmaythereforebesuitablefordiagnosingosteoporosisand forpredictingfracturerisk. 1.Introduction problemthatcalcaneusisnotabonethatfracturesdueto osteoporosis.Ontheotherhand,calcaneusconsistsmainly of trabecular bone and should