role of mesotherapy in musculoskeletal pain opinions from the italian society of mesotherapy消脂的作用在肌肉骨骼疼痛消脂意大利社会的意见.pdfVIP

Hindawi Publishing Corporation Evidence-Based Complementary and Alternative Medicine Volume 2012, Article ID 436959, 12 pages doi:10.1155/2012/436959 Review Article Role of Mesotherapy in Musculoskeletal Pain: Opinions from the Italian Society of Mesotherapy Massimo Mammucari,1 Antonio Gatti,2 Sergio Maggiori,1 and Alessandro F. Sabato2 1 The Italian Society of Mesotherapy, Rome, Italy 2 Emergency Care, Department of Intensive Care, Pain Medicine, and Anaesthesiology, Tor Vergata Polyclinic, University of Tor Vergata, 00133 Rome, Italy Correspondence should be addressed to Massimo Mammucari, massimo.mammucari@libero.it Received 6 November 2011; Revised 5 February 2012; Accepted 24 February 2012 Academic Editor: Adair Roberto Soares Santos Copyright © 2012 Massimo Mammucari et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Mesotherapy is the injection of active substances into the surface layer of the skin. This method allows a slower spread, higher levels, and longer lasting effects of drugs in the tissues underlying the site of injection (skin, muscle, and joint) compared with those following intramuscular injection. This technique is useful when a local pharmacological effect is required and relatively high doses of drug in the systemic circulation are not. Mesotherapy should only be undertaken following a complete clinical workup and subsequent diagnosis. Encouraging results have been reported in randomized, controlled clinical trials and in observational studies involving patients with various forms of musculoskeletal pain. Recommendations by experts from the Italian Society of Mesothe