孕妇血清皮质醇水平对围生儿体格发育的影响.docVIP

精品论文 参考文献 孕妇血清皮质醇水平对围生儿体格发育的影响 葛新梅 冯国惠 　　新疆自治区人民医院 产科 830000 　　摘要：目的：探讨孕妇血清皮质醇水平与围生儿体格发育的关系。方法：应用化学发光法检测正常孕妇及不同程度妊娠高血压疾病患者血清皮质醇含量。记录出生时新生儿体重、头围、身长，计算张路指数。结果：妊娠高血压综合征孕妇血清皮质醇水平明显高于正常对照组，随着妊娠高血压综合征的病情严重程度的增加，血清皮质醇水平明显增加，各组间血清皮质醇水平均有显著性差异（plt;0.05）。患者血清皮质醇水平高低与围生儿张路指数相对趋势分析程负相关，差异具有显著性。结论：随着妊高征病情程度的加重，血清皮质醇水平增高；患者血清皮质醇水平越高，围生儿体格发育状况越差。早期检测孕妇血清皮质醇水平，对妊高症程度及围生儿体格发育早期的预测及评估具有一定的临床意义。 　　关键词：妊娠高血压综合征；皮质醇；围生儿；体格发育；张路指数 　　[pick to]objective：to study the physical development in pregnant women serum cortisol levels and perinatals.Methods：the application of chemiluminescence detection normal pregnant women and patients with pregnancy-induced hypertension disease different level of serum cortisol levels.Record at birth the newborn weight，head circumference，body length，zhang lu4 index calculation.Results：pregnancy-induced hypertension syndrome pregnant women serum cortisol levels are significantly higher than the normal control group，with the increase of the illness severity of pregnancy-induced hypertension syndrome，serum cortisol levels increased significantly，serum cortisol levels were significant differences between groups（p lt; 0.05）.Zhang lu4 in patients with serum cortisol levels and perinatals index relative trend analysis process is negatively related，with significant difference.Conclusion：with the pregnancy，high character degree aggravating illness，increased serum cortisol levels；Patients with higher serum cortisol levels，wai physique growth situation worse.Early detection of pregnant women serum cortisol levels of physical development in degree of pih and perinatals early prediction and evaluation has a certain clinical significance. 　　[key words]pregnancy-induced hypertension syndrome，cortisol，surround begat，physical development，zhang lu4 index 　　妊娠高血压疾病是孕妇特有而又常见的病症，按其严重程度分为妊娠期高血压、子痫前期、子痫，是影响孕产妇和围生儿发病率及死亡率的主要原因[1]。近年来，人们越来越重视围产期保健，随着对妊娠高血压综合征发病因素及机制的进一步研究，血清皮质醇水平对妊娠高血压综合征血压的影响受到重视，血清皮质醇水平对妊娠高血压综合征孕妇母体及胎儿的健康影响逐渐引起人们的关注。本实验采用化学发光法检测正常孕妇及不同程度妊高征患者血清皮质醇水平，研究孕妇血清皮质醇水平对围生